소프트렌즈 재질 별 누액단백질 침착 및 계면활성제종류에 따른 다목적용액의 세척효율

The present study was aimed to investigate the cleaning efficacy of multi-purpose solutions containingdifferent types and content of surfactants and their effect on the visible light transmittance of soft lens. Methods:Soft lenses made of different materials (etafilcon A and hilafilcon B) were deposited tear proteins by using theartificial tear and then compared the resulting cleaning efficacy and visible light transmittance after cleaning thelens with 6 types of multi-purpose solutions containing different content of surfactants. Results: The cleaningefficacy of multi-purpose solutions was variously shown as approximately 23~43% according to the activeconcentration of surfactants and surface tension in multi-purpose solution when etafilcon A lens cleaned withrubbing. The highest cleaning efficacy was detected when cleaned with the multi-purpose solution containinghydrogen peroxide besides surfactant however, the amount of remaining protein was still high on the lens. Afterwashed with multi-purpose solution, the visible light transmittance of lens was in 89.8 to 90.8%. The amount ofprotein deposited on hilafilcon B lens was very small compared with it on etafilcon A lens even though it wasincubated in artificial tears for 7 days, which showed 5~10% of protein amount in etafilcon A lens and thedecrease of visible light transmittance was also not significant. In case of rubbing with multi-purpose solution, thecleaning efficacy on hilafilcon B lens was in 45.4 to 67.4% however, the order of cleaning efficacy of multipurposesolution was different from it on etafilcon A lens. The visible light transmittance of hilafilcon B lens hasbeen restored to the level of new lens. Conclusions: From the result, it is concluded that the appropriate multipurposesolution should be selected according to the lens material and the amount of protein deposit on the basisof understanding surfactants and active principle for proper care of protein deposit on soft lens and the cleaningwith rubbing is more efficient for lens care regardless of manufacturer’s guideline.