콘택트렌즈 재질 및 침착 단백질에 따른 균 흡착 정도와다목적용액의 살균력 비교

Purpose: The present study was aimed to compare the difference in adherence level of microorganisms accordingto contact lens materials and protein deposition and to evaluate disinfection efficacy of multipurpose solution.
Methods: The evaluations of micro-organisms' adherence and disinfection efficacy of multi-purpose solutionwere conducted by employing the Part 2. Regimen Procedure for Disinfecting Regiments in the DisinfectionEfficacy Testing under the “FDA Evaluation Criteria & Method”. Results: Pseudomonas aeruginosa, Serratiamarcescens, Candida albicans except Staphylococcus aureus adhered more on etafilcon A lens and disinfectionefficacy of total 4 products investigated was almost perfect except Candida albicans. The 3 micro-organismsexcept Serratia marcescens adhered more to albumin-predeposited lens. Disinfection efficacy of multi-purposesolution was higher against the micro-organisms adhered to albumin-deposited lens than against the microorganismsadhered to the lysozyme-deposited lens. Furthermore, disinfection efficacy of multi-purpose solutionwas different according to types of micro-organisms. Conclusions: It was revealed that the type of microorganisms,the lens materials and type of absorbed tear protein affected the amount of adhered micro-organismsto contact lens and that adhesion of tear protein could induce the change of disinfection efficacy of multi-purposesolution. It suggest that the hygienic condition of contact lens can vary by these factors influencing ondisinfection efficacy and the occurrence of adverse effect can be affected.