클로르헥시딘 글루콘산염이 포함된 인공눈물이 소프트콘택트렌즈안정성에 미치는 영향

Purpose: This study aimed to investigate the effects of an artificial tear containing chlorhexidine gluconate as a preservative on the parameters and physical properties of soft contact lenses. Methods: After exposing each FDA Group II and Group IV hydrogel lenses, silicone hydrogel lens, and circle soft contact lens with pigmentation on the front surface to undiluted artificial tears for 8 h, the changes in physical properties and parameters of the soft contact lenses were evaluated according to the ophthalmic drug standard manufacturing criteria and medical device standards of the Korea Ministry of Food and Drug Safety. Additionally, the surface and pigmented portion of the circle soft contact lens were examined for deformation. Results: There were no statistically significant changes observed in the color, refractive power, visible light and UV transmittance, overall diameter, base curve, central thickness, water content, oxygen transmissibility, or tensile force of any of the lenses exposed to the artificial tear. No changes, such as blurring, smearing, irregularities, dye clumping, or shifting in the pigmented portions of the circle soft contact lens, were observed. Conclusions: This study confirmed that artificial tear containing chlorhexidine gluconate tested in this experiment did not cause changes in the parameters or physical properties of the soft contact lenses, including circle lenses, when applied while wearing the lenses, in accordance with the ophthalmic drug standard manufacturing criteria and medical device standards of the Ministry of Food and Drug Safety.