A dual chemosensor for Zn2+ and Co2+ in aqueous media and living cells: Experimental and theoretical studies

Gyeong Jin Park; Jae Jun Lee; Ga Rim You; Letuyen Nguyen; Insup Noh; Cheal Kim

doi:10.1016/j.snb.2015.09.129

A dual chemosensor for Zn²⁺ and Co²⁺ in aqueous media and living cells: Experimental and theoretical studies

Gyeong Jin Park, Jae Jun Lee, Ga Rim You, Letuyen Nguyen, Insup Noh, Cheal Kim

Seoul National University of Science and Technology (SNUST)

Research output: Contribution to journal › Article › peer-review

70 Scopus citations

Abstract

A new versatile 'dual' chemosensor 1 has been synthesized for Zn²⁺ and Co²⁺. The sensor 1 comprises of quinoline as a fluorophore and N¹,N¹-dimethylethane-1,2-diamine as a water-soluble functional group. Sensor 1 showed a remarkable fluorescence enhancement in the presence of Zn²⁺ in aqueous solution. The sensor 1 also acted as a colorimetric sensor for Co²⁺ by changing its color from colorless to yellow. Importantly, the chemosensor 1 could be used to quantify Zn²⁺ and Co²⁺ in water samples and to image and quantify Zn²⁺ in living cells. Moreover, the sensing mechanisms of 1 for Zn²⁺ and Co²⁺ were supported by theoretical calculations. Therefore, this sensor has the ability to be a practical system for monitoring Zn²⁺ and Co²⁺ concentrations in biological systems and aqueous samples.

Original language	English
Pages (from-to)	509-519
Number of pages	11
Journal	Sensors and Actuators, B: Chemical
Volume	223
DOIs	https://doi.org/10.1016/j.snb.2015.09.129
State	Published - 1 Feb 2016

Keywords

Cell imaging
Chemosensor
Colorimetric
Determination of Co ion
Determination of Zn ion
Fluorescence

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title = "A dual chemosensor for Zn2+ and Co2+ in aqueous media and living cells: Experimental and theoretical studies",

abstract = "A new versatile 'dual' chemosensor 1 has been synthesized for Zn2+ and Co2+. The sensor 1 comprises of quinoline as a fluorophore and N1,N1-dimethylethane-1,2-diamine as a water-soluble functional group. Sensor 1 showed a remarkable fluorescence enhancement in the presence of Zn2+ in aqueous solution. The sensor 1 also acted as a colorimetric sensor for Co2+ by changing its color from colorless to yellow. Importantly, the chemosensor 1 could be used to quantify Zn2+ and Co2+ in water samples and to image and quantify Zn2+ in living cells. Moreover, the sensing mechanisms of 1 for Zn2+ and Co2+ were supported by theoretical calculations. Therefore, this sensor has the ability to be a practical system for monitoring Zn2+ and Co2+ concentrations in biological systems and aqueous samples.",

keywords = "Cell imaging, Chemosensor, Colorimetric, Determination of Co ion, Determination of Zn ion, Fluorescence",

author = "Park, \{Gyeong Jin\} and Lee, \{Jae Jun\} and You, \{Ga Rim\} and Letuyen Nguyen and Insup Noh and Cheal Kim",

year = "2016",

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doi = "10.1016/j.snb.2015.09.129",

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T1 - A dual chemosensor for Zn2+ and Co2+ in aqueous media and living cells

T2 - Experimental and theoretical studies

AU - Park, Gyeong Jin

AU - Lee, Jae Jun

AU - You, Ga Rim

AU - Nguyen, Letuyen

AU - Noh, Insup

AU - Kim, Cheal

PY - 2016/2/1

Y1 - 2016/2/1

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AB - A new versatile 'dual' chemosensor 1 has been synthesized for Zn2+ and Co2+. The sensor 1 comprises of quinoline as a fluorophore and N1,N1-dimethylethane-1,2-diamine as a water-soluble functional group. Sensor 1 showed a remarkable fluorescence enhancement in the presence of Zn2+ in aqueous solution. The sensor 1 also acted as a colorimetric sensor for Co2+ by changing its color from colorless to yellow. Importantly, the chemosensor 1 could be used to quantify Zn2+ and Co2+ in water samples and to image and quantify Zn2+ in living cells. Moreover, the sensing mechanisms of 1 for Zn2+ and Co2+ were supported by theoretical calculations. Therefore, this sensor has the ability to be a practical system for monitoring Zn2+ and Co2+ concentrations in biological systems and aqueous samples.

KW - Cell imaging

KW - Chemosensor

KW - Colorimetric

KW - Determination of Co ion

KW - Determination of Zn ion

KW - Fluorescence

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ER -

A dual chemosensor for Zn²⁺ and Co²⁺ in aqueous media and living cells: Experimental and theoretical studies

Abstract

Keywords

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