A dual-response sensor based on NBD for the highly selective determination of sulfide in living cells and zebrafish

Ji Hye Kang, Minuk Yang, Dongju Yun, Mingeun Kim, Hyojin Lee, Ki Tae Kim, Mi Hee Lim, Cheal Kim

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

A dual chemosensor, 1-NO2, based on the combination of 4-chloro-7-nitrobenzofurazan (NBD) and 1-(2-hydroxyethyl)piperazine, was applied for the detection of sulfide. Chemosensor 1-NO2 could detect sulfide through fluorescence turn-off and color change from orange to pink-red. The sensing mechanism and structure of 1-NO2 with S2− were demonstrated using Job's plot, ESI-MS analysis and theoretical calculations. In addition, 1-NO2 as a sulfide detector could be used in living organisms (HeLa cells and zebrafish).

Original languageEnglish
Pages (from-to)4029-4035
Number of pages7
JournalNew Journal of Chemistry
Volume43
Issue number10
DOIs
StatePublished - 2019

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