A dual-response sensor based on NBD for the highly selective determination of sulfide in living cells and zebrafish

Ji Hye Kang; Minuk Yang; Dongju Yun; Mingeun Kim; Hyojin Lee; Ki Tae Kim; Mi Hee Lim; Cheal Kim

doi:10.1039/C8NJ06352D

A dual-response sensor based on NBD for the highly selective determination of sulfide in living cells and zebrafish

Ji Hye Kang
, Minuk Yang
, Dongju Yun
, Mingeun Kim
, Hyojin Lee
, Ki Tae Kim
, Mi Hee Lim
, Cheal Kim

Seoul National University of Science and Technology (SNUST)
Korea Advanced Institute of Science and Technology
Ulsan National Institute of Science and Technology

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

A dual chemosensor, 1-NO₂, based on the combination of 4-chloro-7-nitrobenzofurazan (NBD) and 1-(2-hydroxyethyl)piperazine, was applied for the detection of sulfide. Chemosensor 1-NO₂ could detect sulfide through fluorescence turn-off and color change from orange to pink-red. The sensing mechanism and structure of 1-NO₂ with S²⁻ were demonstrated using Job's plot, ESI-MS analysis and theoretical calculations. In addition, 1-NO₂ as a sulfide detector could be used in living organisms (HeLa cells and zebrafish).

Original language	English
Pages (from-to)	4029-4035
Number of pages	7
Journal	New Journal of Chemistry
Volume	43
Issue number	10
DOIs	https://doi.org/10.1039/C8NJ06352D
State	Published - 2019

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@article{e492c62b1c7149c58baf7a1a37b1f82f,

title = "A dual-response sensor based on NBD for the highly selective determination of sulfide in living cells and zebrafish",

abstract = "A dual chemosensor, 1-NO2, based on the combination of 4-chloro-7-nitrobenzofurazan (NBD) and 1-(2-hydroxyethyl)piperazine, was applied for the detection of sulfide. Chemosensor 1-NO2 could detect sulfide through fluorescence turn-off and color change from orange to pink-red. The sensing mechanism and structure of 1-NO2 with S2− were demonstrated using Job's plot, ESI-MS analysis and theoretical calculations. In addition, 1-NO2 as a sulfide detector could be used in living organisms (HeLa cells and zebrafish).",

author = "Kang, \{Ji Hye\} and Minuk Yang and Dongju Yun and Mingeun Kim and Hyojin Lee and Kim, \{Ki Tae\} and Lim, \{Mi Hee\} and Cheal Kim",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry and the Centre National de la Recherche Scientifique.",

year = "2019",

doi = "10.1039/C8NJ06352D",

language = "English",

volume = "43",

pages = "4029--4035",

journal = "New Journal of Chemistry",

issn = "1144-0546",

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TY - JOUR

T1 - A dual-response sensor based on NBD for the highly selective determination of sulfide in living cells and zebrafish

AU - Kang, Ji Hye

AU - Yang, Minuk

AU - Yun, Dongju

AU - Kim, Mingeun

AU - Lee, Hyojin

AU - Kim, Ki Tae

AU - Lim, Mi Hee

AU - Kim, Cheal

PY - 2019

Y1 - 2019

N2 - A dual chemosensor, 1-NO2, based on the combination of 4-chloro-7-nitrobenzofurazan (NBD) and 1-(2-hydroxyethyl)piperazine, was applied for the detection of sulfide. Chemosensor 1-NO2 could detect sulfide through fluorescence turn-off and color change from orange to pink-red. The sensing mechanism and structure of 1-NO2 with S2− were demonstrated using Job's plot, ESI-MS analysis and theoretical calculations. In addition, 1-NO2 as a sulfide detector could be used in living organisms (HeLa cells and zebrafish).

AB - A dual chemosensor, 1-NO2, based on the combination of 4-chloro-7-nitrobenzofurazan (NBD) and 1-(2-hydroxyethyl)piperazine, was applied for the detection of sulfide. Chemosensor 1-NO2 could detect sulfide through fluorescence turn-off and color change from orange to pink-red. The sensing mechanism and structure of 1-NO2 with S2− were demonstrated using Job's plot, ESI-MS analysis and theoretical calculations. In addition, 1-NO2 as a sulfide detector could be used in living organisms (HeLa cells and zebrafish).

UR - https://www.scopus.com/pages/publications/85062439741

U2 - 10.1039/C8NJ06352D

DO - 10.1039/C8NJ06352D

M3 - Article

AN - SCOPUS:85062439741

SN - 1144-0546

VL - 43

SP - 4029

EP - 4035

JO - New Journal of Chemistry

JF - New Journal of Chemistry

IS - 10

ER -

A dual-response sensor based on NBD for the highly selective determination of sulfide in living cells and zebrafish

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