A dual-response sensor based on NBD for the highly selective determination of sulfide in living cells and zebrafish

  • Ji Hye Kang
  • , Minuk Yang
  • , Dongju Yun
  • , Mingeun Kim
  • , Hyojin Lee
  • , Ki Tae Kim
  • , Mi Hee Lim
  • , Cheal Kim

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

A dual chemosensor, 1-NO2, based on the combination of 4-chloro-7-nitrobenzofurazan (NBD) and 1-(2-hydroxyethyl)piperazine, was applied for the detection of sulfide. Chemosensor 1-NO2 could detect sulfide through fluorescence turn-off and color change from orange to pink-red. The sensing mechanism and structure of 1-NO2 with S2− were demonstrated using Job's plot, ESI-MS analysis and theoretical calculations. In addition, 1-NO2 as a sulfide detector could be used in living organisms (HeLa cells and zebrafish).

Original languageEnglish
Pages (from-to)4029-4035
Number of pages7
JournalNew Journal of Chemistry
Volume43
Issue number10
DOIs
StatePublished - 2019

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