A dual-response sensor based on NBD for the highly selective determination of sulfide in living cells and zebrafish

Ji Hye Kang; Minuk Yang; Dongju Yun; Mingeun Kim; Hyojin Lee; Ki Tae Kim; Mi Hee Lim; Cheal Kim

doi:10.1039/C8NJ06352D

A dual-response sensor based on NBD for the highly selective determination of sulfide in living cells and zebrafish

Ji Hye Kang, Minuk Yang, Dongju Yun, Mingeun Kim, Hyojin Lee, Ki Tae Kim, Mi Hee Lim, Cheal Kim

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

A dual chemosensor, 1-NO₂, based on the combination of 4-chloro-7-nitrobenzofurazan (NBD) and 1-(2-hydroxyethyl)piperazine, was applied for the detection of sulfide. Chemosensor 1-NO₂ could detect sulfide through fluorescence turn-off and color change from orange to pink-red. The sensing mechanism and structure of 1-NO₂ with S²⁻ were demonstrated using Job's plot, ESI-MS analysis and theoretical calculations. In addition, 1-NO₂ as a sulfide detector could be used in living organisms (HeLa cells and zebrafish).

Original language	English
Pages (from-to)	4029-4035
Number of pages	7
Journal	New Journal of Chemistry
Volume	43
Issue number	10
DOIs	https://doi.org/10.1039/C8NJ06352D
State	Published - 2019

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@article{e492c62b1c7149c58baf7a1a37b1f82f,

title = "A dual-response sensor based on NBD for the highly selective determination of sulfide in living cells and zebrafish",

abstract = "A dual chemosensor, 1-NO2, based on the combination of 4-chloro-7-nitrobenzofurazan (NBD) and 1-(2-hydroxyethyl)piperazine, was applied for the detection of sulfide. Chemosensor 1-NO2 could detect sulfide through fluorescence turn-off and color change from orange to pink-red. The sensing mechanism and structure of 1-NO2 with S2− were demonstrated using Job's plot, ESI-MS analysis and theoretical calculations. In addition, 1-NO2 as a sulfide detector could be used in living organisms (HeLa cells and zebrafish).",

author = "Kang, \{Ji Hye\} and Minuk Yang and Dongju Yun and Mingeun Kim and Hyojin Lee and Kim, \{Ki Tae\} and Lim, \{Mi Hee\} and Cheal Kim",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry and the Centre National de la Recherche Scientifique.",

year = "2019",

doi = "10.1039/C8NJ06352D",

language = "English",

volume = "43",

pages = "4029--4035",

journal = "New Journal of Chemistry",

issn = "1144-0546",

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T1 - A dual-response sensor based on NBD for the highly selective determination of sulfide in living cells and zebrafish

AU - Kang, Ji Hye

AU - Yang, Minuk

AU - Yun, Dongju

AU - Kim, Mingeun

AU - Lee, Hyojin

AU - Kim, Ki Tae

AU - Lim, Mi Hee

AU - Kim, Cheal

PY - 2019

Y1 - 2019

N2 - A dual chemosensor, 1-NO2, based on the combination of 4-chloro-7-nitrobenzofurazan (NBD) and 1-(2-hydroxyethyl)piperazine, was applied for the detection of sulfide. Chemosensor 1-NO2 could detect sulfide through fluorescence turn-off and color change from orange to pink-red. The sensing mechanism and structure of 1-NO2 with S2− were demonstrated using Job's plot, ESI-MS analysis and theoretical calculations. In addition, 1-NO2 as a sulfide detector could be used in living organisms (HeLa cells and zebrafish).

AB - A dual chemosensor, 1-NO2, based on the combination of 4-chloro-7-nitrobenzofurazan (NBD) and 1-(2-hydroxyethyl)piperazine, was applied for the detection of sulfide. Chemosensor 1-NO2 could detect sulfide through fluorescence turn-off and color change from orange to pink-red. The sensing mechanism and structure of 1-NO2 with S2− were demonstrated using Job's plot, ESI-MS analysis and theoretical calculations. In addition, 1-NO2 as a sulfide detector could be used in living organisms (HeLa cells and zebrafish).

UR - https://www.scopus.com/pages/publications/85062439741

U2 - 10.1039/C8NJ06352D

DO - 10.1039/C8NJ06352D

M3 - Article

AN - SCOPUS:85062439741

SN - 1144-0546

VL - 43

SP - 4029

EP - 4035

JO - New Journal of Chemistry

JF - New Journal of Chemistry

IS - 10

ER -

A dual-response sensor based on NBD for the highly selective determination of sulfide in living cells and zebrafish

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