An acridine-based fluorescent sensor for monitoring clo− in water samples and zebrafish

Su Chan Lee; Soyoung Park; Haeri So; Gyudong Lee; Ki Tae Kim; Cheal Kim

doi:10.3390/s20174764

An acridine-based fluorescent sensor for monitoring clo⁻ in water samples and zebrafish

Su Chan Lee, Soyoung Park, Haeri So, Gyudong Lee, Ki Tae Kim, Cheal Kim

Seoul National University of Science and Technology (SNUST)

Research output: Contribution to journal › Letter › peer-review

31 Scopus citations

Abstract

A novel acridine-based fluorescent chemosensor, BK ((E)-2-((acridine-9-ylimino)methyl)-N-benzhydrylhydrazine-1-carbothioamide), for monitoring ClO⁻ was prepared. The sensor BK was synthesized by introducing a new synthetic route of making aldehyde group using formic hydrazide. Probe BK displayed notable fluorescence quenching in the presence of ClO⁻ and showed a great selectivity over other guest analytes. The detection limit was calculated to be 7.65 µM. Additionally, BK was satisfactorily applied for sensing ClO⁻ in water samples and zebrafish.

Original language	English
Article number	4764
Pages (from-to)	1-13
Number of pages	13
Journal	Sensors
Volume	20
Issue number	17
DOIs	https://doi.org/10.3390/s20174764
State	Published - 1 Sep 2020

Keywords

Acridine
Fluorescent chemosensor
Hypochlorite
Theoretical calculations
Zebrafish

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title = "An acridine-based fluorescent sensor for monitoring clo− in water samples and zebrafish",

abstract = "A novel acridine-based fluorescent chemosensor, BK ((E)-2-((acridine-9-ylimino)methyl)-N-benzhydrylhydrazine-1-carbothioamide), for monitoring ClO− was prepared. The sensor BK was synthesized by introducing a new synthetic route of making aldehyde group using formic hydrazide. Probe BK displayed notable fluorescence quenching in the presence of ClO− and showed a great selectivity over other guest analytes. The detection limit was calculated to be 7.65 µM. Additionally, BK was satisfactorily applied for sensing ClO− in water samples and zebrafish.",

keywords = "Acridine, Fluorescent chemosensor, Hypochlorite, Theoretical calculations, Zebrafish",

author = "Lee, \{Su Chan\} and Soyoung Park and Haeri So and Gyudong Lee and Kim, \{Ki Tae\} and Cheal Kim",

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AU - Lee, Su Chan

AU - Park, Soyoung

AU - So, Haeri

AU - Lee, Gyudong

AU - Kim, Ki Tae

AU - Kim, Cheal

PY - 2020/9/1

Y1 - 2020/9/1

N2 - A novel acridine-based fluorescent chemosensor, BK ((E)-2-((acridine-9-ylimino)methyl)-N-benzhydrylhydrazine-1-carbothioamide), for monitoring ClO− was prepared. The sensor BK was synthesized by introducing a new synthetic route of making aldehyde group using formic hydrazide. Probe BK displayed notable fluorescence quenching in the presence of ClO− and showed a great selectivity over other guest analytes. The detection limit was calculated to be 7.65 µM. Additionally, BK was satisfactorily applied for sensing ClO− in water samples and zebrafish.

AB - A novel acridine-based fluorescent chemosensor, BK ((E)-2-((acridine-9-ylimino)methyl)-N-benzhydrylhydrazine-1-carbothioamide), for monitoring ClO− was prepared. The sensor BK was synthesized by introducing a new synthetic route of making aldehyde group using formic hydrazide. Probe BK displayed notable fluorescence quenching in the presence of ClO− and showed a great selectivity over other guest analytes. The detection limit was calculated to be 7.65 µM. Additionally, BK was satisfactorily applied for sensing ClO− in water samples and zebrafish.

KW - Acridine

KW - Fluorescent chemosensor

KW - Hypochlorite

KW - Theoretical calculations

KW - Zebrafish

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EP - 13

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An acridine-based fluorescent sensor for monitoring clo⁻ in water samples and zebrafish

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