An Easy Detection of Sulfide by an Imine-Bond Cleavage-Based Fluorescence Chemosensor: Smartphone and Paper-Strip Applications

Chanwoo Song, Jae Jun Lee, Hyejin Nam, Cheal Kim

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

We designed an imine-bond cleavage-based fluorescent chemosensor CDH ((E)-(5-chloro-2-((3,5-dichloro-2-hydroxybenzylidene)amino)phenyl)(phenyl)methanone) for detecting S2−. The sensor CDH selectively sensed S2− among various anions through fluorescent change. The fluorescent change was cyan turn-on from colorless with a high quantum yield (λex = 427 nm, Φ = 0.486), resulting in strong fluorescent intensity. With the result of Job plot, the reaction of S2− and CDH turned out to be a 1:1 interaction. The detection limit for S2− of CDH was 2.85 µM. The reaction process of S2− by CDH was demonstrated to be imine-bond cleavage through ESI-mass, 1H NMR titration, and theoretical calculations. Additionally, test-strip and smartphone applications were successfully constructed for S2− detection, and these findings revealed that CDH could be effectively utilized for sulfide sensing without sophisticated instruments.

Original languageEnglish
Article number130576
Pages (from-to)669-678
Number of pages10
JournalKorean Journal of Chemical Engineering
Volume42
Issue number3
DOIs
StatePublished - Mar 2025

Keywords

  • DFT calculation
  • Fluorescent chemosensor
  • Imine bond cleavage
  • Smartphone application
  • Sulfide
  • Test strip

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