An Imidazo[1,5-α]Pyridine-Based Fluorometric Chemodosimeter for the Highly Selective Detection of Hypochlorite in Aqueous Media

Suh Mi Hwang; Dongju Yun; Cheal Kim

doi:10.1007/s10895-019-02355-7

An Imidazo[1,5-α]Pyridine-Based Fluorometric Chemodosimeter for the Highly Selective Detection of Hypochlorite in Aqueous Media

Suh Mi Hwang
, Dongju Yun
, Cheal Kim

Dept. of Fine Chemistry

Seoul National University of Science and Technology (SNUST)

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

A new fluorometric chemodosimeter 2-amino-3-(((E)-3-(1-phenylimidazo[1,5-α]pyridin-3-yl)benzylidene)amino)maleonitrile (BPI-MAL) has been designed and synthesized for sensing hypochlorite. BPI-MAL showed a selective turn-on fluorescence for ClO ⁻ through hypochlorite-promoted de-diaminomaleonitrile reaction. It also could detect ClO ⁻ in the presence of various competitive anions including reactive oxygen species. Interestingly, sensor BPI-MAL was successfully applied as a fluorescent test kit for ClO ⁻ determination. The sensing property and mechanism of BPI-MAL toward ClO ⁻ were studied by fluorescence and UV-vis spectroscopy, NMR titration and DFT calculations.

Original language	English
Pages (from-to)	451-459
Number of pages	9
Journal	Journal of Fluorescence
Volume	29
Issue number	2
DOIs	https://doi.org/10.1007/s10895-019-02355-7
State	Published - 15 Mar 2019

Keywords

Fluorescent chemodosimeter
Hypochlorite
Imidazo[1,5-a]pyridine
Test kit
Theoretical calculations

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10.1007/s10895-019-02355-7

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title = "An Imidazo[1,5-α]Pyridine-Based Fluorometric Chemodosimeter for the Highly Selective Detection of Hypochlorite in Aqueous Media",

abstract = " A new fluorometric chemodosimeter 2-amino-3-(((E)-3-(1-phenylimidazo[1,5-α]pyridin-3-yl)benzylidene)amino)maleonitrile (BPI-MAL) has been designed and synthesized for sensing hypochlorite. BPI-MAL showed a selective turn-on fluorescence for ClO − through hypochlorite-promoted de-diaminomaleonitrile reaction. It also could detect ClO − in the presence of various competitive anions including reactive oxygen species. Interestingly, sensor BPI-MAL was successfully applied as a fluorescent test kit for ClO − determination. The sensing property and mechanism of BPI-MAL toward ClO − were studied by fluorescence and UV-vis spectroscopy, NMR titration and DFT calculations.",

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doi = "10.1007/s10895-019-02355-7",

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AU - Hwang, Suh Mi

AU - Yun, Dongju

AU - Kim, Cheal

PY - 2019/3/15

Y1 - 2019/3/15

N2 - A new fluorometric chemodosimeter 2-amino-3-(((E)-3-(1-phenylimidazo[1,5-α]pyridin-3-yl)benzylidene)amino)maleonitrile (BPI-MAL) has been designed and synthesized for sensing hypochlorite. BPI-MAL showed a selective turn-on fluorescence for ClO − through hypochlorite-promoted de-diaminomaleonitrile reaction. It also could detect ClO − in the presence of various competitive anions including reactive oxygen species. Interestingly, sensor BPI-MAL was successfully applied as a fluorescent test kit for ClO − determination. The sensing property and mechanism of BPI-MAL toward ClO − were studied by fluorescence and UV-vis spectroscopy, NMR titration and DFT calculations.

AB - A new fluorometric chemodosimeter 2-amino-3-(((E)-3-(1-phenylimidazo[1,5-α]pyridin-3-yl)benzylidene)amino)maleonitrile (BPI-MAL) has been designed and synthesized for sensing hypochlorite. BPI-MAL showed a selective turn-on fluorescence for ClO − through hypochlorite-promoted de-diaminomaleonitrile reaction. It also could detect ClO − in the presence of various competitive anions including reactive oxygen species. Interestingly, sensor BPI-MAL was successfully applied as a fluorescent test kit for ClO − determination. The sensing property and mechanism of BPI-MAL toward ClO − were studied by fluorescence and UV-vis spectroscopy, NMR titration and DFT calculations.

KW - Fluorescent chemodosimeter

KW - Hypochlorite

KW - Imidazo[1,5-a]pyridine

KW - Test kit

KW - Theoretical calculations

UR - https://www.scopus.com/pages/publications/85060970368

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ER -

An Imidazo[1,5-α]Pyridine-Based Fluorometric Chemodosimeter for the Highly Selective Detection of Hypochlorite in Aqueous Media

Abstract

Keywords

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