An indole-based fluorescent chemosensor for detecting zn2+ in aqueous media and zebrafish

Donghwan Choe; Haeri So; Soyoung Park; Hangyul Lee; Ju Byeong Chae; Jiwon Kim; Ki Tae Kim; Cheal Kim

doi:10.3390/s21165591

An indole-based fluorescent chemosensor for detecting zn²⁺ in aqueous media and zebrafish

Donghwan Choe, Haeri So, Soyoung Park, Hangyul Lee, Ju Byeong Chae, Jiwon Kim, Ki Tae Kim, Cheal Kim

Seoul National University of Science and Technology (SNUST)

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

An indole-based fluorescent chemosensor IH-Sal was synthesized to detect Zn²⁺. IH-Sal displayed a marked fluorescence increment with Zn²⁺. The detection limit (0.41 µM) of IH-Sal for Zn²⁺ was greatly below that suggested by the World Health Organization. IH-Sal can quantify Zn²⁺ in real water samples. More significantly, IH-Sal could determine and depict the presence of Zn²⁺ in zebrafish. The detecting mechanism of IH-Sal toward Zn²⁺ was illustrated by fluorescence and UV–visible spectroscopy, DFT calculations,¹ H NMR titration and ESI mass.

Original language	English
Article number	5591
Journal	Sensors
Volume	21
Issue number	16
DOIs	https://doi.org/10.3390/s21165591
State	Published - 2 Aug 2021

Keywords

Bio-imaging
Calculations
Fluorescent chemosensor
Indole
Zinc ion

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title = "An indole-based fluorescent chemosensor for detecting zn2+ in aqueous media and zebrafish",

abstract = "An indole-based fluorescent chemosensor IH-Sal was synthesized to detect Zn2+. IH-Sal displayed a marked fluorescence increment with Zn2+. The detection limit (0.41 µM) of IH-Sal for Zn2+ was greatly below that suggested by the World Health Organization. IH-Sal can quantify Zn2+ in real water samples. More significantly, IH-Sal could determine and depict the presence of Zn2+ in zebrafish. The detecting mechanism of IH-Sal toward Zn2+ was illustrated by fluorescence and UV–visible spectroscopy, DFT calculations,1 H NMR titration and ESI mass.",

keywords = "Bio-imaging, Calculations, Fluorescent chemosensor, Indole, Zinc ion",

author = "Donghwan Choe and Haeri So and Soyoung Park and Hangyul Lee and Chae, \{Ju Byeong\} and Jiwon Kim and Kim, \{Ki Tae\} and Cheal Kim",

note = "Publisher Copyright: {\textcopyright} 2021 by the authors. Licensee MDPI, Basel, Switzerland.",

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doi = "10.3390/s21165591",

language = "English",

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T1 - An indole-based fluorescent chemosensor for detecting zn2+ in aqueous media and zebrafish

AU - Choe, Donghwan

AU - So, Haeri

AU - Park, Soyoung

AU - Lee, Hangyul

AU - Chae, Ju Byeong

AU - Kim, Jiwon

AU - Kim, Ki Tae

AU - Kim, Cheal

PY - 2021/8/2

Y1 - 2021/8/2

N2 - An indole-based fluorescent chemosensor IH-Sal was synthesized to detect Zn2+. IH-Sal displayed a marked fluorescence increment with Zn2+. The detection limit (0.41 µM) of IH-Sal for Zn2+ was greatly below that suggested by the World Health Organization. IH-Sal can quantify Zn2+ in real water samples. More significantly, IH-Sal could determine and depict the presence of Zn2+ in zebrafish. The detecting mechanism of IH-Sal toward Zn2+ was illustrated by fluorescence and UV–visible spectroscopy, DFT calculations,1 H NMR titration and ESI mass.

AB - An indole-based fluorescent chemosensor IH-Sal was synthesized to detect Zn2+. IH-Sal displayed a marked fluorescence increment with Zn2+. The detection limit (0.41 µM) of IH-Sal for Zn2+ was greatly below that suggested by the World Health Organization. IH-Sal can quantify Zn2+ in real water samples. More significantly, IH-Sal could determine and depict the presence of Zn2+ in zebrafish. The detecting mechanism of IH-Sal toward Zn2+ was illustrated by fluorescence and UV–visible spectroscopy, DFT calculations,1 H NMR titration and ESI mass.

KW - Bio-imaging

KW - Calculations

KW - Fluorescent chemosensor

KW - Indole

KW - Zinc ion

UR - https://www.scopus.com/pages/publications/85113184641

U2 - 10.3390/s21165591

DO - 10.3390/s21165591

M3 - Article

C2 - 34451041

AN - SCOPUS:85113184641

SN - 1424-8220

VL - 21

JO - Sensors

JF - Sensors

IS - 16

M1 - 5591

ER -

An indole-based fluorescent chemosensor for detecting zn²⁺ in aqueous media and zebrafish

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Keywords

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