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Analysis of Thrombus Characteristics Under Shear-Dependent Formation Conditions

  • Seoul National University of Science and Technology (SNUST)
  • Samsung Medical Center, Sungkyunkwan university

Research output: Contribution to journalConference articlepeer-review

Abstract

Thrombus formation and detachment under varying shear conditions significantly impact clinical outcomes such as embolism or occlusion. This study presents a comparative analysis of thrombus properties formed under low and high shear rates using a microfluidic chip with a circular cross-section and stenosis. We analyzed detachment time (DT), detached thrombus area (DTA), and bonding strength, revealing distinct differences between sparse, weak thrombus in low shear conditions and dense, stable thrombus in high shear environments. These findings emphasize the importance of shear-dependent analysis for understanding thrombus stability and cardiovascular risk.

Original languageEnglish
Pages (from-to)231-234
Number of pages4
JournalInternational Conference on Solid-State Sensors, Actuators and Microsystems, Transducers
Issue number2025
DOIs
StatePublished - 2025
Event23rd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2025 - Orlando, United States
Duration: 29 Jun 20253 Jul 2025

Keywords

  • Bonding Strength
  • Detachment Analysis
  • Shear Rates
  • Thrombus Formation

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