Abstract
This research aimed to investigate the bacterial detection through the fluidity change of liposome
layer. Pyranine-encapsulated liposomes were prepared with palmitoyloleoylphosphatidylcholine or with
palmitoyloleoyl phosphatidylglycerol and oleoylhydroxy phosphatidylglycerol. Each liposome contained
Azobenzene-derivatized phosphatidylcholine (AzoPC) as 10 % molar ratio. AzoPC-contained liposome underwent
the configuration change caused by the UV illumination. Only AzoPC-contained PC-liposome layer turned out
more fluid by the interaction with the bacteria. Therefore, the quantitative bacteria-detection was achieved
with the simple UV-exposure.
layer. Pyranine-encapsulated liposomes were prepared with palmitoyloleoylphosphatidylcholine or with
palmitoyloleoyl phosphatidylglycerol and oleoylhydroxy phosphatidylglycerol. Each liposome contained
Azobenzene-derivatized phosphatidylcholine (AzoPC) as 10 % molar ratio. AzoPC-contained liposome underwent
the configuration change caused by the UV illumination. Only AzoPC-contained PC-liposome layer turned out
more fluid by the interaction with the bacteria. Therefore, the quantitative bacteria-detection was achieved
with the simple UV-exposure.
| Original language | English |
|---|---|
| Journal | American Journal of Sciences and Engineering Research |
| Volume | 7 |
| Issue number | 5 |
| State | Published - Sep 2024 |