Cancer chemopreventive effects of lactic acid bacteria

Jong Eun Kim, Ji Yeon Kim, Ki Won Lee, Hyong Joo Lee

Research output: Contribution to journalReview articlepeer-review

52 Scopus citations

Abstract

Lactic acid bacteria (LAB) provide several potential health and nutritional benefits, including improving the nutritional value of food, controlling serum cholesterol levels, and controlling some types of cancer. Numerous in vitro, in vivo, human, and epidemiological studies have provided evidence of the chemopreventive effects of LAB on colon, bladder, liver, breast, and gastric cancers. These effects act via diverse mechanisms, including alteration of the gastrointestinal microflora, enhancement of the host's immune response, and antioxidative and antiproliferative activities. This review discusses the recent progresses on the chemopreventive effects of LAB on specific cancer types and the underlying molecular mechanisms.

Original languageEnglish
Pages (from-to)1227-1235
Number of pages9
JournalJournal of Microbiology and Biotechnology
Volume17
Issue number8
StatePublished - Aug 2007

Keywords

  • Cancer
  • Chemoprevention
  • Lactic acid bacteria

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