TY - JOUR
T1 - Detecting and bioimaging of hypochlorite by a conjugated fluorescent chemosensor based on thioamide
AU - Kim, Ahran
AU - Lee, Minji
AU - Lee, Hangyul
AU - So, Haeri
AU - Jeong, Soomin
AU - Kim, Ki Tae
AU - Kim, Cheal
N1 - Publisher Copyright:
© 2021 Elsevier B.V.
PY - 2021/12/1
Y1 - 2021/12/1
N2 - A novel thioamide-based conjugated probe SNC, (E)-2-((E)-3-(4-(dimethylamino)phenyl)allylidene)-N,N-dimethylhydrazine-1-carbothioamide, has been designed. Probe SNC could selectively recognize ClO- in aqueous media through fluorescence turn-off and sensitively detect ClO- down to 0.90 μM. In addition, successful detection of hypochlorite was achieved for practical applications in living zebrafish and water samples, and the detection limit turned out to be 2.26 μM. Detection process between SNC and hypochlorite was illustrated through UV–Vis spectroscopy, 1H NMR titration, ESI-mass and DFT study.
AB - A novel thioamide-based conjugated probe SNC, (E)-2-((E)-3-(4-(dimethylamino)phenyl)allylidene)-N,N-dimethylhydrazine-1-carbothioamide, has been designed. Probe SNC could selectively recognize ClO- in aqueous media through fluorescence turn-off and sensitively detect ClO- down to 0.90 μM. In addition, successful detection of hypochlorite was achieved for practical applications in living zebrafish and water samples, and the detection limit turned out to be 2.26 μM. Detection process between SNC and hypochlorite was illustrated through UV–Vis spectroscopy, 1H NMR titration, ESI-mass and DFT study.
KW - Chemosensor
KW - Computational theory
KW - Hypochlorite
KW - Thioamide
KW - Zebrafish
UR - http://www.scopus.com/inward/record.url?scp=85114703653&partnerID=8YFLogxK
U2 - 10.1016/j.jphotochem.2021.113531
DO - 10.1016/j.jphotochem.2021.113531
M3 - Article
AN - SCOPUS:85114703653
SN - 1010-6030
VL - 421
JO - Journal of Photochemistry and Photobiology A: Chemistry
JF - Journal of Photochemistry and Photobiology A: Chemistry
M1 - 113531
ER -