Detection of helicobacter pylori DNA in preliminary stage gastric cancer cells

Suw Young Ly; So Dam Yoo; Seung Kyu Chun

doi:10.1097/PAT.0b013e32834e3395

Detection of helicobacter pylori DNA in preliminary stage gastric cancer cells

Suw Young Ly, So Dam Yoo, Seung Kyu Chun

Dept. of Chemical and Biomolecular Engineering

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Aims: Helicobacter pylori (HP) DNA was assayed using a newly fabricated voltammetric handheld circuit equipped with an interfaced graphite pencil electrode (PE) sensor. Methods: Under optimum analytical parameters, the square-wave (SW) stripping detection range attained was 0.1-0.7 mg/L. Results: A relative standard deviation of 1.68% (RSD, n=5) was observed at a 3.2mg/L HP DNA within a 90s accumulation time. Under these conditions, the analytical detection limit approached 0.07 mg/L. Conclusions: The developed methods can be applied to HP assays of preliminary stage gastric cancer patient tissues.

Original language	English
Pages (from-to)	251-254
Number of pages	4
Journal	Pathology
Volume	44
Issue number	3
DOIs	https://doi.org/10.1097/PAT.0b013e32834e3395
State	Published - Apr 2012

Keywords

Gastric cancer
Helicobacter pylori
Voltammetry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1097/PAT.0b013e32834e3395

Cite this

@article{98fd00e581c74d4a8b6e3c876863384f,

title = "Detection of helicobacter pylori DNA in preliminary stage gastric cancer cells",

abstract = "Aims: Helicobacter pylori (HP) DNA was assayed using a newly fabricated voltammetric handheld circuit equipped with an interfaced graphite pencil electrode (PE) sensor. Methods: Under optimum analytical parameters, the square-wave (SW) stripping detection range attained was 0.1-0.7 mg/L. Results: A relative standard deviation of 1.68\% (RSD, n=5) was observed at a 3.2mg/L HP DNA within a 90s accumulation time. Under these conditions, the analytical detection limit approached 0.07 mg/L. Conclusions: The developed methods can be applied to HP assays of preliminary stage gastric cancer patient tissues.",

keywords = "Gastric cancer, Helicobacter pylori, Voltammetry",

author = "Ly, \{Suw Young\} and Yoo, \{So Dam\} and Chun, \{Seung Kyu\}",

year = "2012",

month = apr,

doi = "10.1097/PAT.0b013e32834e3395",

language = "English",

volume = "44",

pages = "251--254",

journal = "Pathology",

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TY - JOUR

T1 - Detection of helicobacter pylori DNA in preliminary stage gastric cancer cells

AU - Ly, Suw Young

AU - Yoo, So Dam

AU - Chun, Seung Kyu

PY - 2012/4

Y1 - 2012/4

N2 - Aims: Helicobacter pylori (HP) DNA was assayed using a newly fabricated voltammetric handheld circuit equipped with an interfaced graphite pencil electrode (PE) sensor. Methods: Under optimum analytical parameters, the square-wave (SW) stripping detection range attained was 0.1-0.7 mg/L. Results: A relative standard deviation of 1.68% (RSD, n=5) was observed at a 3.2mg/L HP DNA within a 90s accumulation time. Under these conditions, the analytical detection limit approached 0.07 mg/L. Conclusions: The developed methods can be applied to HP assays of preliminary stage gastric cancer patient tissues.

AB - Aims: Helicobacter pylori (HP) DNA was assayed using a newly fabricated voltammetric handheld circuit equipped with an interfaced graphite pencil electrode (PE) sensor. Methods: Under optimum analytical parameters, the square-wave (SW) stripping detection range attained was 0.1-0.7 mg/L. Results: A relative standard deviation of 1.68% (RSD, n=5) was observed at a 3.2mg/L HP DNA within a 90s accumulation time. Under these conditions, the analytical detection limit approached 0.07 mg/L. Conclusions: The developed methods can be applied to HP assays of preliminary stage gastric cancer patient tissues.

KW - Gastric cancer

KW - Helicobacter pylori

KW - Voltammetry

UR - https://www.scopus.com/pages/publications/84863657706

U2 - 10.1097/PAT.0b013e32834e3395

DO - 10.1097/PAT.0b013e32834e3395

M3 - Article

AN - SCOPUS:84863657706

SN - 0031-3025

VL - 44

SP - 251

EP - 254

JO - Pathology

JF - Pathology

IS - 3

ER -

Detection of helicobacter pylori DNA in preliminary stage gastric cancer cells

Abstract

Keywords

UN SDGs

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