Dual thermopile integrated microfluidic calorimeter for biochemical thermodynamics

B. S. Kwak; B. S. Kim; H. H. Cho; J. S. Park; H. I. Jung

doi:10.1007/s10404-007-0243-7

Dual thermopile integrated microfluidic calorimeter for biochemical thermodynamics

B. S. Kwak, B. S. Kim, H. H. Cho, J. S. Park, H. I. Jung

Dept. of Mechanical & Automotive Engineering

Yonsei University

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

This article presents a new design of a silicon-based microcalorimeter made with dual thermopiles and a microchannel. The dual thermopile was fabricated with chromium and copper using a microelectromechanical system (MEMS) technique, and the microchannel was made of PDMS using soft-lithography. Each thermopile consists of 26 thermocouple pairs and 50 μm wide electrodes. The total sensitivity of thermopile is 428 μV/K. The dual thermopile system enables the microcalorimeter to acquire reliable data in a rapid and convenient manner because it detects the reaction and reference temperatures simultaneously. This self-compensation allows our device to analyze a few microliters of sample solution without the need for a surrounding adiabatic vacuum.

Original language	English
Pages (from-to)	255-262
Number of pages	8
Journal	Microfluidics and Nanofluidics
Volume	5
Issue number	2
DOIs	https://doi.org/10.1007/s10404-007-0243-7
State	Published - Aug 2008

Keywords

Biochemical reaction
Calorimeter
Dual thermopile
Microchannel

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s10404-007-0243-7

Cite this

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title = "Dual thermopile integrated microfluidic calorimeter for biochemical thermodynamics",

abstract = "This article presents a new design of a silicon-based microcalorimeter made with dual thermopiles and a microchannel. The dual thermopile was fabricated with chromium and copper using a microelectromechanical system (MEMS) technique, and the microchannel was made of PDMS using soft-lithography. Each thermopile consists of 26 thermocouple pairs and 50 μm wide electrodes. The total sensitivity of thermopile is 428 μV/K. The dual thermopile system enables the microcalorimeter to acquire reliable data in a rapid and convenient manner because it detects the reaction and reference temperatures simultaneously. This self-compensation allows our device to analyze a few microliters of sample solution without the need for a surrounding adiabatic vacuum.",

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AU - Kwak, B. S.

AU - Kim, B. S.

AU - Cho, H. H.

AU - Park, J. S.

AU - Jung, H. I.

PY - 2008/8

Y1 - 2008/8

N2 - This article presents a new design of a silicon-based microcalorimeter made with dual thermopiles and a microchannel. The dual thermopile was fabricated with chromium and copper using a microelectromechanical system (MEMS) technique, and the microchannel was made of PDMS using soft-lithography. Each thermopile consists of 26 thermocouple pairs and 50 μm wide electrodes. The total sensitivity of thermopile is 428 μV/K. The dual thermopile system enables the microcalorimeter to acquire reliable data in a rapid and convenient manner because it detects the reaction and reference temperatures simultaneously. This self-compensation allows our device to analyze a few microliters of sample solution without the need for a surrounding adiabatic vacuum.

AB - This article presents a new design of a silicon-based microcalorimeter made with dual thermopiles and a microchannel. The dual thermopile was fabricated with chromium and copper using a microelectromechanical system (MEMS) technique, and the microchannel was made of PDMS using soft-lithography. Each thermopile consists of 26 thermocouple pairs and 50 μm wide electrodes. The total sensitivity of thermopile is 428 μV/K. The dual thermopile system enables the microcalorimeter to acquire reliable data in a rapid and convenient manner because it detects the reaction and reference temperatures simultaneously. This self-compensation allows our device to analyze a few microliters of sample solution without the need for a surrounding adiabatic vacuum.

KW - Biochemical reaction

KW - Calorimeter

KW - Dual thermopile

KW - Microchannel

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ER -

Dual thermopile integrated microfluidic calorimeter for biochemical thermodynamics

Abstract

Keywords

UN SDGs

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