Abstract
We present expectation-maximization (EM) algorithms for fitting multivariate Gaussian mixture models to data that are truncated, censored or truncated and censored. These two types of incomplete measurements are naturally handled together through their relation to the multivariate truncated Gaussian distribution. We illustrate our algorithms on synthetic and flow cytometry data.
Original language | English |
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Pages (from-to) | 2816-2829 |
Number of pages | 14 |
Journal | Computational Statistics and Data Analysis |
Volume | 56 |
Issue number | 9 |
DOIs | |
State | Published - Sep 2012 |
Keywords
- Censoring
- EM algorithm
- Multivariate Gaussian mixture model
- Multivariate truncated Gaussian distribution
- Truncation