Endolysin-based biocontrol strategies against Listeria monocytogenes in food: A comprehensive review

Dong Woo Kim; Min Suk Kong; Ok Kyung Koo

doi:10.1007/s10068-025-01849-4

Endolysin-based biocontrol strategies against Listeria monocytogenes in food: A comprehensive review

Dong Woo Kim, Min Suk Kong, Ok Kyung Koo

Dept. of Food Science and Technology

Chungnam National University

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

Listeria monocytogenes poses significant challenges in the food industry due to its resistance in harsh environments and its ability to form biofilms. Endolysins represent a promising solution for controlling L. monocytogenes in the food industry, with potential applications during both production and storage. This review discusses various endolysins that effectively inhibit L. monocytogenes, emphasizing their optimal conditions and potential uses in food products. When used in combination with current methods such as nisin or high hydrostatic pressure, endolysins enhance food safety by providing synergistic antimicrobial effects. Additionally, cell binding domain enabled specific and rapid L. monocytogenes detection, expanding diagnostic applications through fluorescence tagging and biosensor integration. Advances in engineering endolysins have further improved their lytic efficiency and specificity, making them adaptable to diverse food safety challenges.

Original language	English
Journal	Food Science and Biotechnology
DOIs	https://doi.org/10.1007/s10068-025-01849-4
State	Accepted/In press - 2025

Keywords

Biocontrol
Endolysin
Food safety
L. monocytogenes
Rapid detection method

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10.1007/s10068-025-01849-4

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title = "Endolysin-based biocontrol strategies against Listeria monocytogenes in food: A comprehensive review",

abstract = "Listeria monocytogenes poses significant challenges in the food industry due to its resistance in harsh environments and its ability to form biofilms. Endolysins represent a promising solution for controlling L. monocytogenes in the food industry, with potential applications during both production and storage. This review discusses various endolysins that effectively inhibit L. monocytogenes, emphasizing their optimal conditions and potential uses in food products. When used in combination with current methods such as nisin or high hydrostatic pressure, endolysins enhance food safety by providing synergistic antimicrobial effects. Additionally, cell binding domain enabled specific and rapid L. monocytogenes detection, expanding diagnostic applications through fluorescence tagging and biosensor integration. Advances in engineering endolysins have further improved their lytic efficiency and specificity, making them adaptable to diverse food safety challenges.",

keywords = "Biocontrol, Endolysin, Food safety, L. monocytogenes, Rapid detection method",

author = "Kim, \{Dong Woo\} and Kong, \{Min Suk\} and Koo, \{Ok Kyung\}",

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year = "2025",

doi = "10.1007/s10068-025-01849-4",

language = "English",

journal = "Food Science and Biotechnology",

issn = "1226-7708",

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TY - JOUR

T1 - Endolysin-based biocontrol strategies against Listeria monocytogenes in food

T2 - A comprehensive review

AU - Kim, Dong Woo

AU - Kong, Min Suk

AU - Koo, Ok Kyung

N1 - Publisher Copyright: © The Korean Society of Food Science and Technology 2025.

PY - 2025

Y1 - 2025

N2 - Listeria monocytogenes poses significant challenges in the food industry due to its resistance in harsh environments and its ability to form biofilms. Endolysins represent a promising solution for controlling L. monocytogenes in the food industry, with potential applications during both production and storage. This review discusses various endolysins that effectively inhibit L. monocytogenes, emphasizing their optimal conditions and potential uses in food products. When used in combination with current methods such as nisin or high hydrostatic pressure, endolysins enhance food safety by providing synergistic antimicrobial effects. Additionally, cell binding domain enabled specific and rapid L. monocytogenes detection, expanding diagnostic applications through fluorescence tagging and biosensor integration. Advances in engineering endolysins have further improved their lytic efficiency and specificity, making them adaptable to diverse food safety challenges.

AB - Listeria monocytogenes poses significant challenges in the food industry due to its resistance in harsh environments and its ability to form biofilms. Endolysins represent a promising solution for controlling L. monocytogenes in the food industry, with potential applications during both production and storage. This review discusses various endolysins that effectively inhibit L. monocytogenes, emphasizing their optimal conditions and potential uses in food products. When used in combination with current methods such as nisin or high hydrostatic pressure, endolysins enhance food safety by providing synergistic antimicrobial effects. Additionally, cell binding domain enabled specific and rapid L. monocytogenes detection, expanding diagnostic applications through fluorescence tagging and biosensor integration. Advances in engineering endolysins have further improved their lytic efficiency and specificity, making them adaptable to diverse food safety challenges.

KW - Biocontrol

KW - Endolysin

KW - Food safety

KW - L. monocytogenes

KW - Rapid detection method

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U2 - 10.1007/s10068-025-01849-4

DO - 10.1007/s10068-025-01849-4

M3 - Review article

AN - SCOPUS:105000445154

SN - 1226-7708

JO - Food Science and Biotechnology

JF - Food Science and Biotechnology

ER -

Endolysin-based biocontrol strategies against Listeria monocytogenes in food: A comprehensive review

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Keywords

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