Exploring the Influence of Mucin on Lipid Bilayers: Insights into Phase-Dependent Interactions

Jin Won Park

doi:10.56557/bn%2F2024%2Fv44i11983

Exploring the Influence of Mucin on Lipid Bilayers: Insights into Phase-Dependent Interactions

Jin Won Park

Dept. of Chemical and Biomolecular Engineering

Research output: Contribution to journal › Article › peer-review

Abstract

Changes in the behavior of the prepared lipid bilayer according to each phase of the layer, induced by mucin incorporation, were investigated. 8-Aminonaphtalene-1,3,6-trisulfonic acid disodium salt (ANTS) was encapsulated only in the water-soluble interior of the vesicle. p-xylene-bis(N-pyridinium bromide) (DPX) settled only outside of the vesicles to quench the ANTS. The calibration was established for the fluorescence with the encapsulated ANTS separated from the DPX (100%) and the ANTS mixed with DPX (0%). The changes were found due to the layer phase over the ratio of mucin to lipid. The changes are determined by the stability of the vesicles.

Original language	English
Pages (from-to)	11-15
Number of pages	5
Journal	Bionature
Volume	44
Issue number	1
DOIs	https://doi.org/10.56557/bn%2F2024%2Fv44i11983
State	Published - Mar 2024

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title = "Exploring the Influence of Mucin on Lipid Bilayers: Insights into Phase-Dependent Interactions",

abstract = "Changes in the behavior of the prepared lipid bilayer according to each phase of the layer, induced by mucin incorporation, were investigated. 8-Aminonaphtalene-1,3,6-trisulfonic acid disodium salt (ANTS) was encapsulated only in the water-soluble interior of the vesicle. p-xylene-bis(N-pyridinium bromide) (DPX) settled only outside of the vesicles to quench the ANTS. The calibration was established for the fluorescence with the encapsulated ANTS separated from the DPX (100\%) and the ANTS mixed with DPX (0\%). The changes were found due to the layer phase over the ratio of mucin to lipid. The changes are determined by the stability of the vesicles.",

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AB - Changes in the behavior of the prepared lipid bilayer according to each phase of the layer, induced by mucin incorporation, were investigated. 8-Aminonaphtalene-1,3,6-trisulfonic acid disodium salt (ANTS) was encapsulated only in the water-soluble interior of the vesicle. p-xylene-bis(N-pyridinium bromide) (DPX) settled only outside of the vesicles to quench the ANTS. The calibration was established for the fluorescence with the encapsulated ANTS separated from the DPX (100%) and the ANTS mixed with DPX (0%). The changes were found due to the layer phase over the ratio of mucin to lipid. The changes are determined by the stability of the vesicles.

U2 - 10.56557/bn%2F2024%2Fv44i11983

DO - 10.56557/bn%2F2024%2Fv44i11983

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SP - 11

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JO - Bionature

JF - Bionature

IS - 1

ER -

Exploring the Influence of Mucin on Lipid Bilayers: Insights into Phase-Dependent Interactions

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