Facile, template-free synthesis of stimuli-responsive polymer nanocapsules for targeted drug delivery

Eunju Kim; Dongwoo Kim; Hyuntae Jung; Jiyeong Lee; Somak Paul; Narayanan Selvapalam; Yosep Yang; Namseok Lim; Chan Gyung Park; Kimoon Kim

doi:10.1002/anie.201000818

Facile, template-free synthesis of stimuli-responsive polymer nanocapsules for targeted drug delivery

Eunju Kim, Dongwoo Kim, Hyuntae Jung, Jiyeong Lee, Somak Paul, Narayanan Selvapalam, Yosep Yang, Namseok Lim, Chan Gyung Park, Kimoon Kim

Dept. of Civil Engineering

Pohang University of Science and Technology

Research output: Contribution to journal › Article › peer-review

194 Scopus citations

Abstract

(Figure Presented) Open Sesame! A synthetic approach to stimuli-responsive polymer nanocapsules has been developed. The reductively labile polymer nanocapsule allows for not only facile, noncovalent surface modification but also the release of encapsulated cargo in response to a predefined redox stimulus in an intracellular environment.

Original language	English
Pages (from-to)	4405-4408
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	49
Issue number	26
DOIs	https://doi.org/10.1002/anie.201000818
State	Published - 14 Jun 2010

Keywords

Cucurbituril
Host-guest systems
Nanostructures
Polymerization
Supramolecular chemistry

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10.1002/anie.201000818

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abstract = "(Figure Presented) Open Sesame! A synthetic approach to stimuli-responsive polymer nanocapsules has been developed. The reductively labile polymer nanocapsule allows for not only facile, noncovalent surface modification but also the release of encapsulated cargo in response to a predefined redox stimulus in an intracellular environment.",

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AU - Kim, Eunju

AU - Kim, Dongwoo

AU - Jung, Hyuntae

AU - Lee, Jiyeong

AU - Paul, Somak

AU - Selvapalam, Narayanan

AU - Yang, Yosep

AU - Lim, Namseok

AU - Park, Chan Gyung

AU - Kim, Kimoon

PY - 2010/6/14

Y1 - 2010/6/14

N2 - (Figure Presented) Open Sesame! A synthetic approach to stimuli-responsive polymer nanocapsules has been developed. The reductively labile polymer nanocapsule allows for not only facile, noncovalent surface modification but also the release of encapsulated cargo in response to a predefined redox stimulus in an intracellular environment.

AB - (Figure Presented) Open Sesame! A synthetic approach to stimuli-responsive polymer nanocapsules has been developed. The reductively labile polymer nanocapsule allows for not only facile, noncovalent surface modification but also the release of encapsulated cargo in response to a predefined redox stimulus in an intracellular environment.

KW - Cucurbituril

KW - Host-guest systems

KW - Nanostructures

KW - Polymerization

KW - Supramolecular chemistry

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U2 - 10.1002/anie.201000818

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M3 - Article

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JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 26

ER -

Facile, template-free synthesis of stimuli-responsive polymer nanocapsules for targeted drug delivery

Abstract

Keywords

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