Facile, template-free synthesis of stimuli-responsive polymer nanocapsules for targeted drug delivery

Eunju Kim; Dongwoo Kim; Hyuntae Jung; Jiyeong Lee; Somak Paul; Narayanan Selvapalam; Yosep Yang; Namseok Lim; Chan Gyung Park; Kimoon Kim

doi:10.1002/anie.201000818

Facile, template-free synthesis of stimuli-responsive polymer nanocapsules for targeted drug delivery

Eunju Kim
, Dongwoo Kim
, Hyuntae Jung
, Jiyeong Lee
, Somak Paul
, Narayanan Selvapalam
, Yosep Yang
, Namseok Lim
, Chan Gyung Park
, Kimoon Kim

Dept. of Civil Engineering

Pohang University of Science and Technology

Research output: Contribution to journal › Article › peer-review

195 Scopus citations

Abstract

(Figure Presented) Open Sesame! A synthetic approach to stimuli-responsive polymer nanocapsules has been developed. The reductively labile polymer nanocapsule allows for not only facile, noncovalent surface modification but also the release of encapsulated cargo in response to a predefined redox stimulus in an intracellular environment.

Original language	English
Pages (from-to)	4405-4408
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	49
Issue number	26
DOIs	https://doi.org/10.1002/anie.201000818
State	Published - 14 Jun 2010

Keywords

Cucurbituril
Host-guest systems
Nanostructures
Polymerization
Supramolecular chemistry

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10.1002/anie.201000818

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title = "Facile, template-free synthesis of stimuli-responsive polymer nanocapsules for targeted drug delivery",

abstract = "(Figure Presented) Open Sesame! A synthetic approach to stimuli-responsive polymer nanocapsules has been developed. The reductively labile polymer nanocapsule allows for not only facile, noncovalent surface modification but also the release of encapsulated cargo in response to a predefined redox stimulus in an intracellular environment.",

keywords = "Cucurbituril, Host-guest systems, Nanostructures, Polymerization, Supramolecular chemistry",

author = "Eunju Kim and Dongwoo Kim and Hyuntae Jung and Jiyeong Lee and Somak Paul and Narayanan Selvapalam and Yosep Yang and Namseok Lim and Park, \{Chan Gyung\} and Kimoon Kim",

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AU - Kim, Eunju

AU - Kim, Dongwoo

AU - Jung, Hyuntae

AU - Lee, Jiyeong

AU - Paul, Somak

AU - Selvapalam, Narayanan

AU - Yang, Yosep

AU - Lim, Namseok

AU - Park, Chan Gyung

AU - Kim, Kimoon

PY - 2010/6/14

Y1 - 2010/6/14

N2 - (Figure Presented) Open Sesame! A synthetic approach to stimuli-responsive polymer nanocapsules has been developed. The reductively labile polymer nanocapsule allows for not only facile, noncovalent surface modification but also the release of encapsulated cargo in response to a predefined redox stimulus in an intracellular environment.

AB - (Figure Presented) Open Sesame! A synthetic approach to stimuli-responsive polymer nanocapsules has been developed. The reductively labile polymer nanocapsule allows for not only facile, noncovalent surface modification but also the release of encapsulated cargo in response to a predefined redox stimulus in an intracellular environment.

KW - Cucurbituril

KW - Host-guest systems

KW - Nanostructures

KW - Polymerization

KW - Supramolecular chemistry

UR - https://www.scopus.com/pages/publications/77953653736

U2 - 10.1002/anie.201000818

DO - 10.1002/anie.201000818

M3 - Article

C2 - 20468019

AN - SCOPUS:77953653736

SN - 1433-7851

VL - 49

SP - 4405

EP - 4408

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 26

ER -

Facile, template-free synthesis of stimuli-responsive polymer nanocapsules for targeted drug delivery

Abstract

Keywords

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