In vitro and vivo application of a rhodanine-based fluorescence sensor for detection and bioimaging of In3+ at neutral pH

Minuk Yang; Jae Jun Lee; Dongju Yun; Haeri So; Yelim Yi; Mi Hee Lim; Hyojin Lee; Ki Tae Kim; Cheal Kim

doi:10.1016/j.jphotochem.2022.114249

In vitro and vivo application of a rhodanine-based fluorescence sensor for detection and bioimaging of In³⁺ at neutral pH

Minuk Yang, Jae Jun Lee, Dongju Yun, Haeri So, Yelim Yi, Mi Hee Lim, Hyojin Lee, Ki Tae Kim, Cheal Kim

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

A rhodanine-based fluorescence chemosensor HTO, 3-((2-hydroxybenzylidene)amino)-2-thioxothiazolidin-4-one, was prepared by the reaction of a 3-aminorhodanine and a salicylaldehyde for detecting In³⁺. HTO could detect In³⁺ with turn-on fluorescence in a near-perfect aqueous media. Detection limit was calculated to be 1.69 μM and the binding feature of HTO with In³⁺ was determined to be 1:1 by Job plot and ESI-mass. The sensing behavior of HTO toward In³⁺ was proposed by using photophysical experiments, ESI-mass and theoretical calculations. In a very rare case, HTO was successfully applied to detect In³⁺ in live organisms (Hela cells and zebrafish).

Original language	English
Article number	114249
Journal	Journal of Photochemistry and Photobiology A: Chemistry
Volume	434
DOIs	https://doi.org/10.1016/j.jphotochem.2022.114249
State	Published - 1 Jan 2023

Keywords

Calculations
Fluorescence chemosensor
Hela cell
Indium
Rhodanine
Zebrafish

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10.1016/j.jphotochem.2022.114249

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title = "In vitro and vivo application of a rhodanine-based fluorescence sensor for detection and bioimaging of In3+ at neutral pH",

abstract = "A rhodanine-based fluorescence chemosensor HTO, 3-((2-hydroxybenzylidene)amino)-2-thioxothiazolidin-4-one, was prepared by the reaction of a 3-aminorhodanine and a salicylaldehyde for detecting In3+. HTO could detect In3+ with turn-on fluorescence in a near-perfect aqueous media. Detection limit was calculated to be 1.69 μM and the binding feature of HTO with In3+ was determined to be 1:1 by Job plot and ESI-mass. The sensing behavior of HTO toward In3+ was proposed by using photophysical experiments, ESI-mass and theoretical calculations. In a very rare case, HTO was successfully applied to detect In3+ in live organisms (Hela cells and zebrafish).",

keywords = "Calculations, Fluorescence chemosensor, Hela cell, Indium, Rhodanine, Zebrafish",

author = "Minuk Yang and Lee, \{Jae Jun\} and Dongju Yun and Haeri So and Yelim Yi and Lim, \{Mi Hee\} and Hyojin Lee and Kim, \{Ki Tae\} and Cheal Kim",

note = "Publisher Copyright: {\textcopyright} 2022 Elsevier B.V.",

year = "2023",

month = jan,

day = "1",

doi = "10.1016/j.jphotochem.2022.114249",

language = "English",

volume = "434",

journal = "Journal of Photochemistry and Photobiology A: Chemistry",

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TY - JOUR

T1 - In vitro and vivo application of a rhodanine-based fluorescence sensor for detection and bioimaging of In3+ at neutral pH

AU - Yang, Minuk

AU - Lee, Jae Jun

AU - Yun, Dongju

AU - So, Haeri

AU - Yi, Yelim

AU - Lim, Mi Hee

AU - Lee, Hyojin

AU - Kim, Ki Tae

AU - Kim, Cheal

PY - 2023/1/1

Y1 - 2023/1/1

N2 - A rhodanine-based fluorescence chemosensor HTO, 3-((2-hydroxybenzylidene)amino)-2-thioxothiazolidin-4-one, was prepared by the reaction of a 3-aminorhodanine and a salicylaldehyde for detecting In3+. HTO could detect In3+ with turn-on fluorescence in a near-perfect aqueous media. Detection limit was calculated to be 1.69 μM and the binding feature of HTO with In3+ was determined to be 1:1 by Job plot and ESI-mass. The sensing behavior of HTO toward In3+ was proposed by using photophysical experiments, ESI-mass and theoretical calculations. In a very rare case, HTO was successfully applied to detect In3+ in live organisms (Hela cells and zebrafish).

AB - A rhodanine-based fluorescence chemosensor HTO, 3-((2-hydroxybenzylidene)amino)-2-thioxothiazolidin-4-one, was prepared by the reaction of a 3-aminorhodanine and a salicylaldehyde for detecting In3+. HTO could detect In3+ with turn-on fluorescence in a near-perfect aqueous media. Detection limit was calculated to be 1.69 μM and the binding feature of HTO with In3+ was determined to be 1:1 by Job plot and ESI-mass. The sensing behavior of HTO toward In3+ was proposed by using photophysical experiments, ESI-mass and theoretical calculations. In a very rare case, HTO was successfully applied to detect In3+ in live organisms (Hela cells and zebrafish).

KW - Calculations

KW - Fluorescence chemosensor

KW - Hela cell

KW - Indium

KW - Rhodanine

KW - Zebrafish

UR - http://www.scopus.com/inward/record.url?scp=85137284811&partnerID=8YFLogxK

U2 - 10.1016/j.jphotochem.2022.114249

DO - 10.1016/j.jphotochem.2022.114249

M3 - Article

AN - SCOPUS:85137284811

SN - 1010-6030

VL - 434

JO - Journal of Photochemistry and Photobiology A: Chemistry

JF - Journal of Photochemistry and Photobiology A: Chemistry

M1 - 114249

ER -

In vitro and vivo application of a rhodanine-based fluorescence sensor for detection and bioimaging of In³⁺ at neutral pH

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Keywords

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