Microfluidic Thormbus Analysis System

Ji Seob Choi, Dong Hwi Ham, Jin Ho Choi, Woo Tae Park

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The aim of this study is to investigate thrombus formation under varying wall shear rates (WSR), using a microfluidic chip-based system. We utilized a microfluidic chip with a circular cross-section that replicates the WSR distribution found in human vessels as our thrombus model. Real-time monitoring of the thrombus development process, including accumulation and lysis, was conducted, and quantitative analysis was performed through image processing to confirm the results. Additionally, activated platelets under high shear rates were further observed through post-morphology analysis using Scanning Electron Microscope (SEM).

Original languageEnglish
Title of host publication2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1352-1355
Number of pages4
ISBN (Electronic)9784886864352
StatePublished - 2023
Event22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023 - Kyoto, Japan
Duration: 25 Jun 202329 Jun 2023

Publication series

Name2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023

Conference

Conference22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023
Country/TerritoryJapan
CityKyoto
Period25/06/2329/06/23

Keywords

  • Blood Experiment
  • Image Analysis
  • Microfluidic Chip
  • Thrombosis

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