Nanoliter reactor arrays for antibiotic study

Jin Won Park

doi:10.5012/bkcs.2007.28.10.1709

Nanoliter reactor arrays for antibiotic study

Jin Won Park

Dept. of Chemical and Biomolecular Engineering

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

It is demonstrated in this study that the nanoliter reactor arrays with an inkjet printing, can be used for high throughput screen of antibiotic function. As a model antibiotic, gramicidin was used in this study. The gramicidin embedded lipid vesicles were immobilized on the surface in the nanoliter reactor structure with control of the volume in the nanoliter reactor. By dispensing acidic drops into the reactor, the gramicidin function was monitored. The technique developed in this research also has a great potential to be used for discovery of drugs.

Original language	English
Pages (from-to)	1709-1714
Number of pages	6
Journal	Bulletin of the Korean Chemical Society
Volume	28
Issue number	10
DOIs	https://doi.org/10.5012/bkcs.2007.28.10.1709
State	Published - 20 Oct 2007

Keywords

Arrays
Gramicidin
Nanoliter
Reactor
Vesicles

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10.5012/bkcs.2007.28.10.1709

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AB - It is demonstrated in this study that the nanoliter reactor arrays with an inkjet printing, can be used for high throughput screen of antibiotic function. As a model antibiotic, gramicidin was used in this study. The gramicidin embedded lipid vesicles were immobilized on the surface in the nanoliter reactor structure with control of the volume in the nanoliter reactor. By dispensing acidic drops into the reactor, the gramicidin function was monitored. The technique developed in this research also has a great potential to be used for discovery of drugs.

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KW - Gramicidin

KW - Nanoliter

KW - Reactor

KW - Vesicles

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Nanoliter reactor arrays for antibiotic study

Abstract

Keywords

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