Novel circular microchannels fabrication method for artery thrombosis investigation

Thanh Qua Nguyen; Sang Youp Lee; Woo Tae Park

doi:10.1109/MEMSYS.2018.8346559

Novel circular microchannels fabrication method for artery thrombosis investigation

Thanh Qua Nguyen, Sang Youp Lee, Woo Tae Park

Dept. of Mechanical & Automotive Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

2 Scopus citations

Abstract

This paper demonstrates the straightforward fabrication process of polydimethylsiloxane (PDMS) circular cross-section microfluidic channels by using air pressure to define the deformation of partially cured PDMS surface. Based on this technique, circular cross-section microchannel can be easily produced in a wide range of dimensions from 100 μm to 500 μm with simple bench top equipment. Using self-alignment and bonding with partially cured PDMS, this technique can eliminate air plasma activated bonding and tedious alignment processes. We successfully used the technique to fabricate multiple dimensions of circular microchannels to mimic the artery for investigating artery thrombosis phenomenon on a chip.

Original language	English
Title of host publication	2018 IEEE Micro Electro Mechanical Systems, MEMS 2018
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	352-354
Number of pages	3
ISBN (Electronic)	9781538647820
DOIs	https://doi.org/10.1109/MEMSYS.2018.8346559
State	Published - 24 Apr 2018
Event	31st IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2018 - Belfast, United Kingdom Duration: 21 Jan 2018 → 25 Jan 2018

Publication series

Name	Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Volume	2018-January
ISSN (Print)	1084-6999

Conference

Conference	31st IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2018
Country/Territory	United Kingdom
City	Belfast
Period	21/01/18 → 25/01/18

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10.1109/MEMSYS.2018.8346559

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Nguyen, T. Q., Lee, S. Y., & Park, W. T. (2018). Novel circular microchannels fabrication method for artery thrombosis investigation. In 2018 IEEE Micro Electro Mechanical Systems, MEMS 2018 (pp. 352-354). (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS); Vol. 2018-January). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MEMSYS.2018.8346559

@inproceedings{edc72aed0e654b23a0e8a38f2659f694,

title = "Novel circular microchannels fabrication method for artery thrombosis investigation",

abstract = "This paper demonstrates the straightforward fabrication process of polydimethylsiloxane (PDMS) circular cross-section microfluidic channels by using air pressure to define the deformation of partially cured PDMS surface. Based on this technique, circular cross-section microchannel can be easily produced in a wide range of dimensions from 100 μm to 500 μm with simple bench top equipment. Using self-alignment and bonding with partially cured PDMS, this technique can eliminate air plasma activated bonding and tedious alignment processes. We successfully used the technique to fabricate multiple dimensions of circular microchannels to mimic the artery for investigating artery thrombosis phenomenon on a chip.",

author = "Nguyen, \{Thanh Qua\} and Lee, \{Sang Youp\} and Park, \{Woo Tae\}",

note = "Publisher Copyright: {\textcopyright} 2018 IEEE.; 31st IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2018 ; Conference date: 21-01-2018 Through 25-01-2018",

year = "2018",

month = apr,

day = "24",

doi = "10.1109/MEMSYS.2018.8346559",

language = "English",

series = "Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

pages = "352--354",

booktitle = "2018 IEEE Micro Electro Mechanical Systems, MEMS 2018",

}

Nguyen, TQ, Lee, SY & Park, WT 2018, Novel circular microchannels fabrication method for artery thrombosis investigation. in 2018 IEEE Micro Electro Mechanical Systems, MEMS 2018. Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), vol. 2018-January, Institute of Electrical and Electronics Engineers Inc., pp. 352-354, 31st IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2018, Belfast, United Kingdom, 21/01/18. https://doi.org/10.1109/MEMSYS.2018.8346559

Novel circular microchannels fabrication method for artery thrombosis investigation. / Nguyen, Thanh Qua; Lee, Sang Youp; Park, Woo Tae.
2018 IEEE Micro Electro Mechanical Systems, MEMS 2018. Institute of Electrical and Electronics Engineers Inc., 2018. p. 352-354 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS); Vol. 2018-January).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Novel circular microchannels fabrication method for artery thrombosis investigation

AU - Nguyen, Thanh Qua

AU - Lee, Sang Youp

AU - Park, Woo Tae

PY - 2018/4/24

Y1 - 2018/4/24

N2 - This paper demonstrates the straightforward fabrication process of polydimethylsiloxane (PDMS) circular cross-section microfluidic channels by using air pressure to define the deformation of partially cured PDMS surface. Based on this technique, circular cross-section microchannel can be easily produced in a wide range of dimensions from 100 μm to 500 μm with simple bench top equipment. Using self-alignment and bonding with partially cured PDMS, this technique can eliminate air plasma activated bonding and tedious alignment processes. We successfully used the technique to fabricate multiple dimensions of circular microchannels to mimic the artery for investigating artery thrombosis phenomenon on a chip.

AB - This paper demonstrates the straightforward fabrication process of polydimethylsiloxane (PDMS) circular cross-section microfluidic channels by using air pressure to define the deformation of partially cured PDMS surface. Based on this technique, circular cross-section microchannel can be easily produced in a wide range of dimensions from 100 μm to 500 μm with simple bench top equipment. Using self-alignment and bonding with partially cured PDMS, this technique can eliminate air plasma activated bonding and tedious alignment processes. We successfully used the technique to fabricate multiple dimensions of circular microchannels to mimic the artery for investigating artery thrombosis phenomenon on a chip.

UR - https://www.scopus.com/pages/publications/85046997793

U2 - 10.1109/MEMSYS.2018.8346559

DO - 10.1109/MEMSYS.2018.8346559

M3 - Conference contribution

AN - SCOPUS:85046997793

T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)

SP - 352

EP - 354

BT - 2018 IEEE Micro Electro Mechanical Systems, MEMS 2018

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 31st IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2018

Y2 - 21 January 2018 through 25 January 2018

ER -

Nguyen TQ, Lee SY, Park WT. Novel circular microchannels fabrication method for artery thrombosis investigation. In 2018 IEEE Micro Electro Mechanical Systems, MEMS 2018. Institute of Electrical and Electronics Engineers Inc. 2018. p. 352-354. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). doi: 10.1109/MEMSYS.2018.8346559

Novel circular microchannels fabrication method for artery thrombosis investigation

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