Optimization of MOF-235 synthesis by analysis of statistical design of experiment

Mingee Chung, Kye Sang Yoo

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Statistical design of experiments was performed to optimize MOF-235 synthesis process. Concentrations of terephthalic acid (TPA), iron (III) chloride hexahydrate, N,N-dimethylformamide (DMF) and ethanol were important factors to develop the crystal structure of MOF-235. MOF-235 was synthesized with various concentrations of the listed chemicals above and the crystallinity was measured by XRD. The effect of the composition on the synthesis of MOF-235 was evaluated using a statistical analysis. For the variance analysis using F-test, the concentration of ethanol showed the greatest effect on the crystallinity and TPA the least influential. A regression model for predicting the crystallinity of MOF-235 was derived and the prediction results for two synthetic variables were presented using contour plots. Finally, the crystallinity was predicted by a mixture method with FeCl3, ethanol and DMF.

Original languageEnglish
Pages (from-to)615-619
Number of pages5
JournalApplied Chemistry for Engineering
Volume30
Issue number5
DOIs
StatePublished - Oct 2019

Keywords

  • Design of experiment
  • MOF-235
  • Statistical optimization

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