Preparation of drug loaded polyurethane thin layer on the silicone tube by electrospinning technique for stent application

D. G. Shin, Y. J. Lee, Y. Kim, W. T. Kwon, S. R. Kim, D. H. Riu

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Drug loaded polyurethane (PU) thin layer was prepared on the silicone tube by electrospinning technique. Microstructure of the PU layer was varied from nanoporous web to dense coating depending on the polymer solution concentration and the amount of drug loaded. It can be easily adjusted the coating thickness and porosity accurately and controlled the drug loading and releasing properties. However, adhesive strength between PU layer and silicone tube was very weak and easily broken away and white turbidity also another important problem. So, surface of silicone tube was atmospheric-pressure plasma (APP) treated for improving the adhesive and removing white turbidity phenomenon.

Original languageEnglish
Title of host publicationEco-Materials Processing and Design XV
EditorsSoo Wohn Lee, Hyung Sun Kim, Banh Tien Long, Jian Feng Yang, Tohru Sekino
PublisherTrans Tech Publications Ltd
Pages131-134
Number of pages4
ISBN (Electronic)9783038352389
DOIs
StatePublished - 2015
Event15th International Symposium on Eco-Materials Processing and Design, ISEPD 2014 - Hanoi, Viet Nam
Duration: 12 Jan 201415 Jan 2014

Publication series

NameMaterials Science Forum
Volume804
ISSN (Print)0255-5476

Conference

Conference15th International Symposium on Eco-Materials Processing and Design, ISEPD 2014
Country/TerritoryViet Nam
CityHanoi
Period12/01/1415/01/14

Keywords

  • APP
  • Coating
  • Drug loading
  • Electrospinning
  • Stent

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