Simultaneous bioimaging recognition of cation Al3+ and anion F- by a fluorogenic method

Yong Sung Kim; Jae Jun Lee; Ye Won Choi; Ga Rim You; Le Tuyen Nguyen; Insup Noh; Cheal Kim

doi:10.1016/j.dyepig.2016.02.016

Simultaneous bioimaging recognition of cation Al³⁺ and anion F^- by a fluorogenic method

Yong Sung Kim
, Jae Jun Lee
, Ye Won Choi
, Ga Rim You
, Le Tuyen Nguyen
, Insup Noh
, Cheal Kim

Seoul National University of Science and Technology (SNUST)

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

A new highly selective and sensitive chemosensor 1 for both Al³⁺ and F^- was designed and synthesized. 1 could detect both Al³⁺ and F^- with turn-on fluorescence behavior in a nearly perfect aqueous solution. The binding stoichiometry of receptor 1 with Al³⁺ and F^- was proposed to be 1:1, respectively, based on Job plot, ¹H NMR titration and ESI-mass spectrometry analysis. The detection limits (1.12 μM for Al³⁺ and 7.01 μM for F^-) of 1 for Al³⁺ and F^- were lower than the World Health Organization guidelines (7.41 μM for Al³⁺ and 79 μM for F^-) for drinking water. Chemosensor 1 was also successfully applied to living cells for simultaneous detection and quantification of both Al³⁺ and F^-. Moreover, the sensing mechanisms of 1 toward Al³⁺ and F^- were explained by theoretical calculations.

Original language	English
Pages (from-to)	43-53
Number of pages	11
Journal	Dyes and Pigments
Volume	129
DOIs	https://doi.org/10.1016/j.dyepig.2016.02.016
State	Published - Jun 2016

Keywords

Aluminum ion
Cell imaging
Fluorescence
Fluoride
Julolidine
Theoretical calculations

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This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.dyepig.2016.02.016

Cite this

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title = "Simultaneous bioimaging recognition of cation Al3+ and anion F- by a fluorogenic method",

abstract = "A new highly selective and sensitive chemosensor 1 for both Al3+ and F- was designed and synthesized. 1 could detect both Al3+ and F- with turn-on fluorescence behavior in a nearly perfect aqueous solution. The binding stoichiometry of receptor 1 with Al3+ and F- was proposed to be 1:1, respectively, based on Job plot, 1H NMR titration and ESI-mass spectrometry analysis. The detection limits (1.12 μM for Al3+ and 7.01 μM for F-) of 1 for Al3+ and F- were lower than the World Health Organization guidelines (7.41 μM for Al3+ and 79 μM for F-) for drinking water. Chemosensor 1 was also successfully applied to living cells for simultaneous detection and quantification of both Al3+ and F-. Moreover, the sensing mechanisms of 1 toward Al3+ and F- were explained by theoretical calculations.",

keywords = "Aluminum ion, Cell imaging, Fluorescence, Fluoride, Julolidine, Theoretical calculations",

author = "Kim, \{Yong Sung\} and Lee, \{Jae Jun\} and Choi, \{Ye Won\} and You, \{Ga Rim\} and Nguyen, \{Le Tuyen\} and Insup Noh and Cheal Kim",

year = "2016",

month = jun,

doi = "10.1016/j.dyepig.2016.02.016",

language = "English",

volume = "129",

pages = "43--53",

journal = "Dyes and Pigments",

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}

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T1 - Simultaneous bioimaging recognition of cation Al3+ and anion F- by a fluorogenic method

AU - Kim, Yong Sung

AU - Lee, Jae Jun

AU - Choi, Ye Won

AU - You, Ga Rim

AU - Nguyen, Le Tuyen

AU - Noh, Insup

AU - Kim, Cheal

PY - 2016/6

Y1 - 2016/6

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AB - A new highly selective and sensitive chemosensor 1 for both Al3+ and F- was designed and synthesized. 1 could detect both Al3+ and F- with turn-on fluorescence behavior in a nearly perfect aqueous solution. The binding stoichiometry of receptor 1 with Al3+ and F- was proposed to be 1:1, respectively, based on Job plot, 1H NMR titration and ESI-mass spectrometry analysis. The detection limits (1.12 μM for Al3+ and 7.01 μM for F-) of 1 for Al3+ and F- were lower than the World Health Organization guidelines (7.41 μM for Al3+ and 79 μM for F-) for drinking water. Chemosensor 1 was also successfully applied to living cells for simultaneous detection and quantification of both Al3+ and F-. Moreover, the sensing mechanisms of 1 toward Al3+ and F- were explained by theoretical calculations.

KW - Aluminum ion

KW - Cell imaging

KW - Fluorescence

KW - Fluoride

KW - Julolidine

KW - Theoretical calculations

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