Smart gold nanoparticle-stabilized ultrasound microbubbles as cancer theranostics

Young Il Yoon; Xin Pang; Sungwook Jung; Guofeng Zhang; Minsuk Kong; Gang Liu; Xiaoyuan Chen

doi:10.1039/c8tb00368h

Smart gold nanoparticle-stabilized ultrasound microbubbles as cancer theranostics

Young Il Yoon
, Xin Pang
, Sungwook Jung
, Guofeng Zhang
, Minsuk Kong
, Gang Liu
, Xiaoyuan Chen

Dept. of Food Science and Technology

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

Smart gold nanoparticle-stabilized microbubbles (SAuMBs) composed of a gas-filled core and shell including smart gold nanoparticles (SAuNPs) which can be aggregated in tumors were applied as ultrasound-mediated cancer theranostics. The gas core in the microstructure enabled the detection of tumors using ultrasound and facilitated the delivery of SAuNPs by sonoporation. The SAuNPs spontaneously aggregated in tumors, which allowed photoacoustic (PA) monitoring and photothermal treatment (PTT) of tumors.

Original language	English
Pages (from-to)	3235-3239
Number of pages	5
Journal	Journal of Materials Chemistry B
Volume	6
Issue number	20
DOIs	https://doi.org/10.1039/c8tb00368h
State	Published - 2018

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SDG 3 Good Health and Well-being

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10.1039/c8tb00368h

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title = "Smart gold nanoparticle-stabilized ultrasound microbubbles as cancer theranostics",

abstract = "Smart gold nanoparticle-stabilized microbubbles (SAuMBs) composed of a gas-filled core and shell including smart gold nanoparticles (SAuNPs) which can be aggregated in tumors were applied as ultrasound-mediated cancer theranostics. The gas core in the microstructure enabled the detection of tumors using ultrasound and facilitated the delivery of SAuNPs by sonoporation. The SAuNPs spontaneously aggregated in tumors, which allowed photoacoustic (PA) monitoring and photothermal treatment (PTT) of tumors.",

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AU - Yoon, Young Il

AU - Pang, Xin

AU - Jung, Sungwook

AU - Zhang, Guofeng

AU - Kong, Minsuk

AU - Liu, Gang

AU - Chen, Xiaoyuan

PY - 2018

Y1 - 2018

N2 - Smart gold nanoparticle-stabilized microbubbles (SAuMBs) composed of a gas-filled core and shell including smart gold nanoparticles (SAuNPs) which can be aggregated in tumors were applied as ultrasound-mediated cancer theranostics. The gas core in the microstructure enabled the detection of tumors using ultrasound and facilitated the delivery of SAuNPs by sonoporation. The SAuNPs spontaneously aggregated in tumors, which allowed photoacoustic (PA) monitoring and photothermal treatment (PTT) of tumors.

AB - Smart gold nanoparticle-stabilized microbubbles (SAuMBs) composed of a gas-filled core and shell including smart gold nanoparticles (SAuNPs) which can be aggregated in tumors were applied as ultrasound-mediated cancer theranostics. The gas core in the microstructure enabled the detection of tumors using ultrasound and facilitated the delivery of SAuNPs by sonoporation. The SAuNPs spontaneously aggregated in tumors, which allowed photoacoustic (PA) monitoring and photothermal treatment (PTT) of tumors.

UR - https://www.scopus.com/pages/publications/85047511763

U2 - 10.1039/c8tb00368h

DO - 10.1039/c8tb00368h

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EP - 3239

JO - Journal of Materials Chemistry B

JF - Journal of Materials Chemistry B

IS - 20

ER -

Smart gold nanoparticle-stabilized ultrasound microbubbles as cancer theranostics

Abstract

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