Smart gold nanoparticle-stabilized ultrasound microbubbles as cancer theranostics

Young Il Yoon, Xin Pang, Sungwook Jung, Guofeng Zhang, Minsuk Kong, Gang Liu, Xiaoyuan Chen

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

Smart gold nanoparticle-stabilized microbubbles (SAuMBs) composed of a gas-filled core and shell including smart gold nanoparticles (SAuNPs) which can be aggregated in tumors were applied as ultrasound-mediated cancer theranostics. The gas core in the microstructure enabled the detection of tumors using ultrasound and facilitated the delivery of SAuNPs by sonoporation. The SAuNPs spontaneously aggregated in tumors, which allowed photoacoustic (PA) monitoring and photothermal treatment (PTT) of tumors.

Original languageEnglish
Pages (from-to)3235-3239
Number of pages5
JournalJournal of Materials Chemistry B
Volume6
Issue number20
DOIs
StatePublished - 2018

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