TY - JOUR
T1 - Solid-State NMR Spectroscopy of Aligned Lipid Bilayers at Low Temperatures
AU - Lee, Dong Kuk
AU - Wildman, Katherine Henzler
AU - Ramamoorthy, Ayyalusamy
PY - 2004/3/3
Y1 - 2004/3/3
N2 - This study, for the first time, demonstrates that it is possible to mechanically align lipid bilayers at a very low temperature (as low as the gel-to-liquid crystalline phase transition temperature). Performing NMR experiments on mechanically aligned lipid bilayers at a low temperature increases the signal-to-noise ratio, the resolution, and the span of NMR parameters. The increased lifetime of the alignment and the nature of the bilayer sample would enhance the application of solid-state NMR techniques to study membrane proteins.
AB - This study, for the first time, demonstrates that it is possible to mechanically align lipid bilayers at a very low temperature (as low as the gel-to-liquid crystalline phase transition temperature). Performing NMR experiments on mechanically aligned lipid bilayers at a low temperature increases the signal-to-noise ratio, the resolution, and the span of NMR parameters. The increased lifetime of the alignment and the nature of the bilayer sample would enhance the application of solid-state NMR techniques to study membrane proteins.
UR - http://www.scopus.com/inward/record.url?scp=1542375007&partnerID=8YFLogxK
U2 - 10.1021/ja039077o
DO - 10.1021/ja039077o
M3 - Article
C2 - 14982431
AN - SCOPUS:1542375007
SN - 0002-7863
VL - 126
SP - 2318
EP - 2319
JO - Journal of the American Chemical Society
JF - Journal of the American Chemical Society
IS - 8
ER -