Structure–Activity Relationship Study of 2,4-Dianilinopyrimidine Containing Methanesulfonamide (TRE-069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment

Hyeonjeong Choe; Byeong Uk Jeon; Myoung Eun Jung; Moon Kook Jeon; Inji Shin; Byoung Chul Cho; Gildon Choi; Chong Hak Chae; Kwangho Lee

doi:10.1002/bkcs.11287

Structure–Activity Relationship Study of 2,4-Dianilinopyrimidine Containing Methanesulfonamide (TRE-069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment

Hyeonjeong Choe
, Byeong Uk Jeon
, Myoung Eun Jung
, Moon Kook Jeon
, Inji Shin
, Byoung Chul Cho
, Gildon Choi
, Chong Hak Chae
, Kwangho Lee

Dept. of Fine Chemistry

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Original language	English
Pages (from-to)	1353-1357
Number of pages	5
Journal	Bulletin of the Korean Chemical Society
Volume	38
Issue number	11
DOIs	https://doi.org/10.1002/bkcs.11287
State	Published - Nov 2017

Keywords

Diaminopyrimidines
Epidermal growth factor receptor T790M/C797S
Kinases
Nonsmall cell lung cancer

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/bkcs.11287

Cite this

Choe, H., Jeon, B. U., Jung, M. E., Jeon, M. K., Shin, I., Cho, B. C., Choi, G., Chae, C. H., & Lee, K. (2017). Structure–Activity Relationship Study of 2,4-Dianilinopyrimidine Containing Methanesulfonamide (TRE-069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment. Bulletin of the Korean Chemical Society, 38(11), 1353-1357. https://doi.org/10.1002/bkcs.11287

@article{d39f07d40f9d41dbbe8cb9d763120f2b,

title = "Structure–Activity Relationship Study of 2,4-Dianilinopyrimidine Containing Methanesulfonamide (TRE-069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment",

keywords = "Diaminopyrimidines, Epidermal growth factor receptor T790M/C797S, Kinases, Nonsmall cell lung cancer",

author = "Hyeonjeong Choe and Jeon, \{Byeong Uk\} and Jung, \{Myoung Eun\} and Jeon, \{Moon Kook\} and Inji Shin and Cho, \{Byoung Chul\} and Gildon Choi and Chae, \{Chong Hak\} and Kwangho Lee",

year = "2017",

month = nov,

doi = "10.1002/bkcs.11287",

language = "English",

volume = "38",

pages = "1353--1357",

journal = "Bulletin of the Korean Chemical Society",

issn = "0253-2964",

number = "11",

}

Choe, H, Jeon, BU, Jung, ME, Jeon, MK, Shin, I, Cho, BC, Choi, G, Chae, CH & Lee, K 2017, 'Structure–Activity Relationship Study of 2,4-Dianilinopyrimidine Containing Methanesulfonamide (TRE-069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment', Bulletin of the Korean Chemical Society, vol. 38, no. 11, pp. 1353-1357. https://doi.org/10.1002/bkcs.11287

Structure–Activity Relationship Study of 2,4-Dianilinopyrimidine Containing Methanesulfonamide (TRE-069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment. / Choe, Hyeonjeong; Jeon, Byeong Uk; Jung, Myoung Eun et al.
In: Bulletin of the Korean Chemical Society, Vol. 38, No. 11, 11.2017, p. 1353-1357.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Structure–Activity Relationship Study of 2,4-Dianilinopyrimidine Containing Methanesulfonamide (TRE-069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment

AU - Choe, Hyeonjeong

AU - Jeon, Byeong Uk

AU - Jung, Myoung Eun

AU - Jeon, Moon Kook

AU - Shin, Inji

AU - Cho, Byoung Chul

AU - Choi, Gildon

AU - Chae, Chong Hak

AU - Lee, Kwangho

PY - 2017/11

Y1 - 2017/11

KW - Diaminopyrimidines

KW - Epidermal growth factor receptor T790M/C797S

KW - Kinases

KW - Nonsmall cell lung cancer

UR - https://www.scopus.com/pages/publications/85031324886

U2 - 10.1002/bkcs.11287

DO - 10.1002/bkcs.11287

M3 - Article

AN - SCOPUS:85031324886

SN - 0253-2964

VL - 38

SP - 1353

EP - 1357

JO - Bulletin of the Korean Chemical Society

JF - Bulletin of the Korean Chemical Society

IS - 11

ER -

Structure–Activity Relationship Study of 2,4-Dianilinopyrimidine Containing Methanesulfonamide (TRE-069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment

Keywords

UN SDGs

Access to Document

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