Structure–Activity Relationship Study of 2,4-Dianilinopyrimidine Containing Methanesulfonamide (TRE-069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment

Hyeonjeong Choe; Byeong Uk Jeon; Myoung Eun Jung; Moon Kook Jeon; Inji Shin; Byoung Chul Cho; Gildon Choi; Chong Hak Chae; Kwangho Lee

doi:10.1002/bkcs.11287

Structure–Activity Relationship Study of 2,4-Dianilinopyrimidine Containing Methanesulfonamide (TRE-069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment

Hyeonjeong Choe
, Byeong Uk Jeon
, Myoung Eun Jung
, Moon Kook Jeon
, Inji Shin
, Byoung Chul Cho
, Gildon Choi
, Chong Hak Chae
, Kwangho Lee

Dept. of Fine Chemistry

Korea Research Institute of Chemical Technology
Korea Advanced Institute of Science and Technology
Sogang University
Yonsei University
University of Science and Technology UST

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Original language	English
Pages (from-to)	1353-1357
Number of pages	5
Journal	Bulletin of the Korean Chemical Society
Volume	38
Issue number	11
DOIs	https://doi.org/10.1002/bkcs.11287
State	Published - Nov 2017

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Diaminopyrimidines
Epidermal growth factor receptor T790M/C797S
Kinases
Nonsmall cell lung cancer

Access to Document

10.1002/bkcs.11287

Cite this

Choe, H., Jeon, B. U., Jung, M. E., Jeon, M. K., Shin, I., Cho, B. C., Choi, G., Chae, C. H., & Lee, K. (2017). Structure–Activity Relationship Study of 2,4-Dianilinopyrimidine Containing Methanesulfonamide (TRE-069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment. Bulletin of the Korean Chemical Society, 38(11), 1353-1357. https://doi.org/10.1002/bkcs.11287

@article{d39f07d40f9d41dbbe8cb9d763120f2b,

title = "Structure–Activity Relationship Study of 2,4-Dianilinopyrimidine Containing Methanesulfonamide (TRE-069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment",

keywords = "Diaminopyrimidines, Epidermal growth factor receptor T790M/C797S, Kinases, Nonsmall cell lung cancer",

author = "Hyeonjeong Choe and Jeon, \{Byeong Uk\} and Jung, \{Myoung Eun\} and Jeon, \{Moon Kook\} and Inji Shin and Cho, \{Byoung Chul\} and Gildon Choi and Chae, \{Chong Hak\} and Kwangho Lee",

year = "2017",

month = nov,

doi = "10.1002/bkcs.11287",

language = "English",

volume = "38",

pages = "1353--1357",

journal = "Bulletin of the Korean Chemical Society",

issn = "0253-2964",

number = "11",

}

Choe, H, Jeon, BU, Jung, ME, Jeon, MK, Shin, I, Cho, BC, Choi, G, Chae, CH & Lee, K 2017, 'Structure–Activity Relationship Study of 2,4-Dianilinopyrimidine Containing Methanesulfonamide (TRE-069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment', Bulletin of the Korean Chemical Society, vol. 38, no. 11, pp. 1353-1357. https://doi.org/10.1002/bkcs.11287

Structure–Activity Relationship Study of 2,4-Dianilinopyrimidine Containing Methanesulfonamide (TRE-069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment. / Choe, Hyeonjeong; Jeon, Byeong Uk; Jung, Myoung Eun et al.
In: Bulletin of the Korean Chemical Society, Vol. 38, No. 11, 11.2017, p. 1353-1357.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Structure–Activity Relationship Study of 2,4-Dianilinopyrimidine Containing Methanesulfonamide (TRE-069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment

AU - Choe, Hyeonjeong

AU - Jeon, Byeong Uk

AU - Jung, Myoung Eun

AU - Jeon, Moon Kook

AU - Shin, Inji

AU - Cho, Byoung Chul

AU - Choi, Gildon

AU - Chae, Chong Hak

AU - Lee, Kwangho

PY - 2017/11

Y1 - 2017/11

KW - Diaminopyrimidines

KW - Epidermal growth factor receptor T790M/C797S

KW - Kinases

KW - Nonsmall cell lung cancer

UR - https://www.scopus.com/pages/publications/85031324886

U2 - 10.1002/bkcs.11287

DO - 10.1002/bkcs.11287

M3 - Article

AN - SCOPUS:85031324886

SN - 0253-2964

VL - 38

SP - 1353

EP - 1357

JO - Bulletin of the Korean Chemical Society

JF - Bulletin of the Korean Chemical Society

IS - 11

ER -

Structure–Activity Relationship Study of 2,4-Dianilinopyrimidine Containing Methanesulfonamide (TRE-069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment

UN SDGs

Keywords

Access to Document

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Cite this