Synthesis and Suzuki-Miyaura cross-coupling reactions of potassium Boc-protected aminomethyltrifluoroborate with aryl and hetaryl halides

Gary A. Molander; Inji Shin

doi:10.1021/ol2014768

Synthesis and Suzuki-Miyaura cross-coupling reactions of potassium Boc-protected aminomethyltrifluoroborate with aryl and hetaryl halides

Gary A. Molander
, Inji Shin

Dept. of Fine Chemistry

University of Pennsylvania

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Abstract

Potassium Boc-protected aminomethyltrifluoroborate, a primary aminomethyl equivalent, was synthesized successfully through a "one-pot" process. With this trifluoroborate, Suzuki-Miyaura cross-coupling reactions were investigated with a variety of both aryl and hetaryl chlorides in good to excellent yields.

Original language	English
Pages (from-to)	3956-3959
Number of pages	4
Journal	Organic Letters
Volume	13
Issue number	15
DOIs	https://doi.org/10.1021/ol2014768
State	Published - 5 Aug 2011

Access to Document

10.1021/ol2014768

Cite this

@article{6d2d99672e9e4358820fc6690c12c0ad,

title = "Synthesis and Suzuki-Miyaura cross-coupling reactions of potassium Boc-protected aminomethyltrifluoroborate with aryl and hetaryl halides",

abstract = "Potassium Boc-protected aminomethyltrifluoroborate, a primary aminomethyl equivalent, was synthesized successfully through a {"}one-pot{"} process. With this trifluoroborate, Suzuki-Miyaura cross-coupling reactions were investigated with a variety of both aryl and hetaryl chlorides in good to excellent yields.",

author = "Molander, \{Gary A.\} and Inji Shin",

year = "2011",

month = aug,

day = "5",

doi = "10.1021/ol2014768",

language = "English",

volume = "13",

pages = "3956--3959",

journal = "Organic Letters",

issn = "1523-7060",

number = "15",

}

TY - JOUR

T1 - Synthesis and Suzuki-Miyaura cross-coupling reactions of potassium Boc-protected aminomethyltrifluoroborate with aryl and hetaryl halides

AU - Molander, Gary A.

AU - Shin, Inji

PY - 2011/8/5

Y1 - 2011/8/5

N2 - Potassium Boc-protected aminomethyltrifluoroborate, a primary aminomethyl equivalent, was synthesized successfully through a "one-pot" process. With this trifluoroborate, Suzuki-Miyaura cross-coupling reactions were investigated with a variety of both aryl and hetaryl chlorides in good to excellent yields.

AB - Potassium Boc-protected aminomethyltrifluoroborate, a primary aminomethyl equivalent, was synthesized successfully through a "one-pot" process. With this trifluoroborate, Suzuki-Miyaura cross-coupling reactions were investigated with a variety of both aryl and hetaryl chlorides in good to excellent yields.

UR - https://www.scopus.com/pages/publications/79961096949

U2 - 10.1021/ol2014768

DO - 10.1021/ol2014768

M3 - Article

C2 - 21732595

AN - SCOPUS:79961096949

SN - 1523-7060

VL - 13

SP - 3956

EP - 3959

JO - Organic Letters

JF - Organic Letters

IS - 15

ER -

Synthesis and Suzuki-Miyaura cross-coupling reactions of potassium Boc-protected aminomethyltrifluoroborate with aryl and hetaryl halides

Abstract

Access to Document

Other files and links

Fingerprint

Cite this